Bernie Wone

Bernie Wone

Assistant Professor

BIOLOGY

Churchill-Haines Labs 170B

Phone: (605) 677-6176

Email: Bernie.Wone@usd.edu

Teaching Interests:

Molecular Biology, Comparative Physiology, Functional Genomics, Advanced Biostatistics.


Research Interests:

Metabolism, Aging, Abiotic Stress, Metabolomics, Physiological Ecology, Comparative Physiology, Physiological Genomics, Transcriptional Regulation


Grants:

  • Crassulacean Acid Metabolism (CAM) Specific Transcription Factor Based Genetic Engineering to Improve Drought Stress Response in C3 Plants, South Dakota Board of Regents. (2017 - Present)

Publications:

Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.

  • Walker, Gabriela, and Wone, Bernard. Towards a Healthy Society: Identifying Socio-Cultural Factors that Might Influence Disabling Addictive Behaviors in Working Populations. In International Journal for Cross-Disciplinary Subjects in Education, Online. Vol. 8, Iss. 4. International Journal for Cross-Disciplinary Subjects in Education, 2017.
  • Yobi, A, Schlauch, K A., Tillet, R L., Yim, W C., Espinosa, C, Wone, B W., Cushman, J C., and Oliver, M J.. Sporobolus stapfianus: Insights into desiccation tolerance in the resurrection grasses from linking transcriptomics to metabolomics. BMC Plant Biology, 2017. (DOI: 10.1186/s12870-017-1013-7)
  • Downs, C J., Brown, J L., Wone, Bernard, Donovan, E R., and Hayes, J P.. Speeding up growth: selection for mass-independent maximal metabolic rate alters growth rates. American Naturalist, 2016.
  • Yang, X, Cushman, J C., Borland, A M., Edwards, E J., Wullschleger, S D., Tusan, G A., Owen, N A., Griffiths, H, Andrews, JA C., De Paoli, H C., Weston, D J., Cottingham, R, Hartwell, J, Davis, S C., Silvera, K, Ming, R, Schlauch, K A., Abraham, P, Stewart, J R., Guo, H B., Albion, R L., Ha, J, Lim, S D., Wone, Bernard, Yim, W C., and et, al. A roadmap for research on crassulacean acid metabolism to enhance sustainable food and bioenergy production in a hotter, drier world, 491-504. Vol. 207. New Phytologist, 2015.
  • Wone, Bernard, Madsen, P, Donovan, E R., Labocha, M K., Sears, M W., Downs, C J., Sorensen, D A., and Hayes, J P.. A strong response to selection on mass-independent maximal metabolic rate without a correlated response in basal metabolic rate, 419-427. Vol. 114. Heredity, 2015. (DOI: 10.1038/hdy.2014.122)
  • Wone, Bernard, Donovan, E R., Cushman, J C., and Hayes, J P.. Metabolic rates associated with membrane fatty acids in mice selected for increased maximal metabolic rate, 70-78. Vol. 165. Comp Biochem Physiol A , 2013.
  • Downs, C J., Brown, J L., Wone, Bernard, Donovan, E R., Hunter, K, and Hayes, J P.. Selection for increased mass-independent maximal metabolic rate suppresses innate but not adaptive immune function, 1471-2954. Vol. 280. Proc R Soc B , 2013.
  • Miller, W W., Johnson, D W., Gergans, N, Carroll-Moore, E M., Walker, R F., Cody, T L., and Wone, Bernard. Update on the effects of a sierran wildfire on surface runoff water quality, 1185-1195. Vol. 42. J Eviron Qual , 2013.
  • Yobi, A, Wone, Bernard, Xu, W, Alexander, D C., Guo, L, Ryals, J A., Oliver, M J., and Cushman, J C.. Comparative metabolic profiling between desiccation-sensitive and desiccation-tolerant species of Selaginella reveals novel insights into the resurrection trait, 399-405. Vol. 72. Plant J, 2012.
  • Yobi, A, Wone, Bernard, Xu, W, Alexander, D C., Guo, L, Ryals, J A., Oliver, M J., and Cushman, J C.. Metabolomic profiling in Selaginella lepidophylla reveals adaptations essential for desiccation tolerance, 369-385. Vol. 6. Mol Plant, 2012.
  • Oliver, M J., Guo, L, Alexander, D C., Ryals, J A., Wone, Bernard, and Cuahman, J C.. A sister group contrast delineates the biochemical regulation underlying desiccation tolerance in Sporobolus stapfianus, 1231-1248. Vol. 23. Plant Cell, 2011.
  • Wone, Bernard, Donovan, E R., and Hayes, J P.. Metabolomics of aerobic metabolism in mice selected for increased maximal metabolic rate, 399-405. Vol. 6. Comp Biochem Physiol D, 2011.
  • Wone, Bernard, Sears, M W., Labocha, M K., Donovan, E R., and Hayes, J P.. Genetic variances and covariances of aerobic metabolic rates in laboratory mice., 3695-3704. Vol. 276. Proc R Soc B, 2009.
  • Wone, Bernard, and Wone, Beate. Movements, home range, and activity patterns of the horned lizard, Phrynosoma mcallii, 679-686. Vol. 37. J Herp, 2003.
  • Wone, Beate, Wone, Bernard, Bros, S, and Kutilek, M. Habitat use of the flat-tailed horned lizard (Phrynosoma mcallii) in a disturbed environment, 210-216. Vol. 32. J Herp, 1998.
  • Wone, Bernard, and Wone, Beate. Observations on the escape behavior of the horned lizard Phrynosoma mcallii, 132. Vol. 26. Herp Review, 1995.
  • Wone, Bernard, Kinchen, Jason M., Kaup, Elana R., and Wone, Beate. A procession of metabolic alterations accompanying muscle senescence in Manduca sexta. Scientific Reports.

Awards and Honors:

  • Research Recognition Award, Comparative and Evolutionary Physiology Section of the American Physiological Society, 2014

Presentations:

  • Walker, Gabriela, Yockey, Mark, Wone, Bernard. Identifying Globalization Factors that Might Lead to Addictive Behaviors Culminating in Disability. Presented at the 16th Annual Hawaii International Conference on Education, Honolulu, Hawaii. (January 4, 2018)
  • Rathnayake, Kumudu N., Koster, Karen, Oliver, Melvin, Alexander, Danny, Wone, Bernard. A comparative metabolomic study between constitutively desiccation tolerant Syntrichia ruralis and inducibly desiccation tolerant Physcomitrella patens. Presented at the International Plant & Animal Genome XXVI, San Diego, CA. (January 2018)
  • Rathnayake, Kumudu N., Koster, Karen, Alexander, Danny, Wone, Bernard. Desiccation Tolerance in the Moss Physcomitrella patens: Insights into Metabolic Pathway Alterations during Acquisition of Desiccation Tolerance.. Presented at the MOSS 2017, Honolulu, HI. (June 23, 2017)
  • Walker, Gabriela, Wone, Bernard. Socio-Cultural Factors Impacting Disabling Addictive Behaviors in Work-Aged Populations. Presented at the Canada International Conference on Education (CICE 2017), University of Toronto Mississauga, Canada. (June 2017)
  • Rathnayake, Kumudu N., Wone, Bernard, Alexander, Danny, Koster, Karen. The Acquisition of Desiccation Tolerance in the Moss Physcomitrella patens: a metabolomic analysis.. Presented at the Plant Biology 2017, Honolulu, HI. (June 2017)
  • Wone, Bernard, Kinchen, Jason M., Swanson, David. Seasonal Metabotypes in Small Birds. Presented at the Experimental Biology Annual Meeting, Chicago, IL. (April 2017)
  • Wone, Beate, Kinchen, Jason M., Kaup, Elana R., Wone, Bernard. Time course metabolic profiling of senescing flight muscles in the hawk moth, Manduca sexta. Presented at the Experimental Biology Annual Meeting. (April 2017)
  • Garcia, T M., Wone, Bernard, Yim, W C., Lim, S D., Ha, J, Schlauch, K A., Cushman, J C.. Characterization of the Transcriptional Regulation of Crassulacean Acid Metabolism (CAM) in Kalanchoe laxiflora mesophyll Tissue. Presented at the International Plant & Animal Genome XXV, San Diego, CA. (January 2017)
  • Yim, W C., Ha, J, Lim, S D., Wone, Bernard, Albion, R L., Yin, H, Yang, X, Cushman, J C.. Genome Sequencing of the Common Ice Plant (Mesembryanthemum crystallinum L.). Presented at the International Plant & Animal Genome XXV, San Diego, CA. (January 2017)
  • Yim, W C., Lim, S D., Wone, Bernard, Albion, R L., Mayer, J A., Cushman, J C.. Transcriptome Analysis & Beyond: Advanced Approaches for Transcriptome Analysis in Diploid and Polyploid Plant Species. Presented at the International Plant & Animal Genome XXV, San Diego, CA. (January 2017)
  • Wone, Beate, Kinchen, Jason M., Kaup, Elana R., Wone, Bernard. Metabolic changes underpinning aging flight muscles in the hawk moth, Manduca sexta. Presented at the American Physiological Society Intersociety Meeting: The Integrative Biology of Exercise , Phoenix, AZ. (November 2016)
  • Meyer, J A., Yim, W C., Wone, Bernard, Patterson, A H., Cushman, J C.. Generating a Robust Genome and Transcriptome for Prickly Pear Cactus. Presented at the International Plant & Animal Genome XXIV, San Diego, CA. (January 2016)
  • Yim, W C., Lim, S D., Ha, J, Wone, Bernard, Albion, R L., Cushman, J C., Yin, H, Yang, X. High Quality De Novo Genome Assemblies of the Common Ice Plant (Mesembryanthemum crystallinum L.) - a Functional Genomics Resource for Crassulacean Acid Metabolism (CAM) and Halophytism. Presented at the International Plant & Animal Genome XXIV, San Diego, CA. (January 2016)
  • Wone, Bernard. Covariates, random effects, false discovery rates and beyond. Presented at the 9th International Congress of Comparative Physiology and Biochemistry, Kraków, Poland. (August 2015)
  • Wone, Bernard, Bilgi, B G., Schlauch, K A., Cushman, J C.. Metabolome dynamics of crassulacean acid metabolism (CAM) in the facultative CAM species, Mesembryanthemum crystallinum. Presented at the 20th Penn State Plant Biology Symposium, Plant Stress-Omics in a Changing Climate, Penn State, State College, PA. (April 2015)
  • Wone, Bernard, Ojha, J, Davidowitz, G. Animal models of human muscle aging and disease: the hawk moth, Manduca sexta, flies forward. Presented at the Experimental Biology Annual Meeting, Boston, MA. (March 2015)
  • Wone, Bernard, Yim, W C., Albion, R L., Schlauch, K A., Cushman, J C.. Uncovering transcriptional gene regulatory networks operating in the facultative CAM species, Mesembryanthemum crystallinum. Presented at the International Plant & Animal Genome XXII, San Diego, CA. (January 2015)
  • Wone, Bernard, Ojha, J, Davidowitz, G. Age related changes in flight muscle ultrastructures of the hawk moth, Manduca sexta: a novel non-vertebrate animal model for investigating vertebrate skeletal muscle function, disease, degeneration, and aging. Presented at the American Physiological Society Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology, San Diego, CA. (October 2014)
  • Wone, Bernard, Bilgi, B G., Albion, R L., Yim, W C., Tillet, R L., Schlauch, K A., Cushman, J C.. Transcriptional dynamics of crassulacean acid metabolism (CAM) in the facultative CAM species, Mesembryanthemum crystallinum. Presented at the 34th New Phytologist Symposium: Systems biology and ecology of CAM plants, Tahoe City, CA. (July 2014)
  • Wone, Bernard, Ojha, J, Contreras, H L., Davidowitz, G. More is not always better: a hidden cost of the flight-fecundity trade-off in the hawk moth. Presented at the Experimental Biology Annual Meeting, San Diego, CA. (April 2014)
  • Wone, Bernard, Bilgi, B G., Albion, R L., Yim, W C., Schlauch, K A., Cushman, J C.. Transcriptomic and Metabolomic Analysis of CAM in Ice Plant. Presented at the International Plant & Animal Genome XXII, Functional Genomics of C4 and CAM Photosynthesis workshop, San Diego, CA. (January 2014)
  • Wone, Bernard, Schlauch, K A., Cushman, J C.. Identifying temporal regulatory networks operating within mesophyll cells in a CAM plant. Presented at the International Symposium on C4 and CAM Plant Biology, Champaign, IL. (August 2013)