Scott Pattison

Scott Pattison

Assistant Professor

BASIC BIOMEDICAL SCIENCES

Lee Medicine & Science Hall 349

Phone: (605) 658-6385

Email: Scott.Pattison@usd.edu

Teaching Interests:

cardiac biology, skeletal muscle physiology, cell biology, molecular biology, exercise physiology


Research Interests:

Autophagy, Cardiac biology, skeletal muscle plasticity, aging


Education:

  • Ph D, Biomedical Sciences, University of Missouri, 2004
  • BA, Biology, Wabash College, 1997

Grants:

  • CMA-targeting peptide technology as a novel therapeutic approach to combat disease-causing mutant proteins, USD U. Discover Scholar Program. Grant Role: Principal. (2016 - 2016)
  • Testing Chaperone-Mediated Autophagy-Targeting Peptide Technology, USD. Grant Role: Supporting. (2015 - 2016)
  • Defining p62 as a regulator of proteasomal function and composition in the cardiomyocyte, Sanford School of Medicine. Grant Role: Principal. (2015 - 2016)
  • Defining the role of p62 phosphorylation on CryABR120G aggregation in cardiomyocytes., SSOM. Grant Role: Principal. (2014 - 2015)
  • Testing the Sufficiency of Atg7 to Protect Hearts from Ischemia-Induced Myocardial Infarction, SSOM. (2013 - 2014)
  • Defining the Sufficiency of Atg7 to suppress Phenylephrine-induced Cardiac Hypertrophy., SD-BRIN. Grant Role: Principal. (2012 - 2013)
  • DEFINING THE ROLE OF P62 IN PROTEASOMAL INHIBITION AND HEART FAILURE, USD-OSRP. Grant Role: Principal. (2012 - 2013)
  • Determining if Atg7 and Cathespin D Synergistically Activate Autophagy, Sanford School of Medicine. Grant Role: Principal. (2012 - 2013)
  • U. Discover Scholar Program, USD. Grant Role: Supporting. (2012 - 2012)
  • The Effect of Cathepsin D on Misfolded Protein Patology in Diseased Cardiomyocytes, USD-OSRP. Grant Role: Principal. (2012 - 2012)

Publications:

Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.

  • Klionski, Daniel J., and Pattison, James S.. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition), 1-222. Vol. 12, Iss. 1. Taylor and Francis: Autophagy, 2016.
  • Bhuiyan, Md s., Pattison, James S., Osinska, Hanna, James, Jeanne, Gulick, James, McLendon, Patrick M., Hill, Joseph A., Sadoshima, Junichi, and Robbins, Jeffrey. Enhanced autophagy ameliorates cardiac proteinopathy.. Edited by Howard Rockman, 5284-5297. Vol. 123, Iss. 12. Ann Arbor, MI: Journal of Clinical Investigation, 2013. (DOI: 10.1172/JCI70877)
  • Wang, Xuejun, Pattison, James S., and Su, Huabo. Posttranslational Modification and Quality Control, 367-381. Vol. 112, Iss. 2. Circulation Research, 2013. (DOI: 10.1161/CIRCRESAHA.112.268706)
  • Wang, Xuejun, Pattison, James S., and Su, Huabo. Posttranslational Modification and Quality Control, 367-381. PMID: 23329792 [PubMed] . Vol. 112, Iss. 2. Circulation Research, 2013. (DOI: 10.1161/CIRCRESAHA.112.268706)
  • Pattison, James S.. Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis, 545-553. Vol. 15, Iss. 4. Cell Metabolism, 2012.

Presentations:

  • Pattison, James S., Freeling, Jessica L.. Increased Atg7 Expression in the Heart Enhances Cardiac Function. Presented at the Nebraska Physiological Society Meeting, Vermillion. (October 11, 2015)
  • Pattison, James S., Tjeerdsma, Marcus, Froke, Levi, Freeling, Jessica. Defining the Sufficiency of Atg7 to Suppress Phenylephrine-induced Cardiac Hypertrophy.. Presented at the Scientific Sessions, Chicago, IL. (November 17, 2014)
  • Richards, Jaime, Pattison, James S.. Testing the Effects of p62 Phosphorylation in Neonatal Cardiomyocytes.
  • Froke, Levi, Tjeerdsma, Marcus, Pattison, James S.. Defining the Role of p62 Phosphorylation on Cardiomyocyte Proteotoxicity. Presented at the Third Annual Symposium on Ubiquitin, Protein Quality Control, and Molecular Pathogenesis, Deadwood, SD. (June 5, 2014)
  • Pattison, James S.. p62-dependent Proteotoxicity and Cardiac Pathology. Presented at the Third annual PQCD Symposia, Deadwood, SD. (June 4, 2014)
  • Pattison, James S.. Defining the Role of p62 in Cardiac Hypertrophy and Pathology. Presented at the Scientific Sessions, Los Angeles. (November 5, 2012)
  • Pattison, James S.. Induced basal autophagy in Atg7 mice ameliorates cardiac proteinopathy. Presented at the Scientific Sessions, Los Angeles, CA. (November 5, 2012)