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Contact Information:
Division of Basic Biomedical Sciences
Sanford School of Medicine of The University of South Dakota
414 E.Clark Street
Vermillion, SD 57069
phone: (605)-677-5254
fax: (605)-677-6381
biomed@usd.edu
Last Modified: 05/11/09
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Barry G. Timms, Ph.D. (University of Wales, U.K)
Professor
Reproductive Biology
(605) 677-5144
btimms@usd.edu
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Dr. Timms studies prostate growth and development - the complex ductal architecture of the gland during fetal development - using sophisticated 3-dimensional computerized serial section reconstruction. Current research focuses on two main areas: a) the cellular mechanisms controlling proliferation and differentiation of the prostate, and b) the effect of environmental endocrine disruptors on glandular growth patterns.
Timms BG. 2008. Prostate development: A historical perspective. Differentiation. 76:565-577.
Hofkamp L, Bradley S, Tresguerres J, Lichtensteiger W, Schlumpf M, Timms B. 2008. Region-Specific Growth Effects in the Developing Rat Prostate Following Fetal Exposure to Estrogenic UV Filters. Environ. Health Perspect. 116:867-872.
Schlumpf M, Durrer S, Faass O, Ehnes C, Fuetsch M, Gaille C, Henseler M, Hofkamp L, Maerkel K, Reolon S, Timms B, Tresguerres JA, Lichtensteiger W. 2008. Developmental toxicity of UV filters and environmental exposure: a review. Int J. of Androl. 31:144-151
Timms BG, Howdeshell KL, Barton L, Bradley S, Richter C and vom Saal FS, 2005. Estrogenic Chemicals in plastic and oral contraceptives alter development of the fetal mouse prostate and urethra. Proc. Nat. Acad. Sci. 102:7014-7019. http://www.pnas.org/cgi/content/full/102/19/7014
Timms BG, Howdeshell KL, Barton L, Bradley S, Richter C and vom Saal FS, 2005. Estrogenic Chemicals in plastic and oral contraceptives alter development of the fetal mouse prostate and urethra. Proc. Nat. Acad. Sci. 102:7014-7019. http://www.pnas.org/cgi/content/full/102/19/7014
Vom Saal FS, Richter CA, Ruhlen RR, Nagel SC, Timms BG, Welshons WV (2005). The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A. Birth Defects Res. Part A: Clin. Mol. Teratol. 73:140-5.
Bostwick DG, Burke HB, Djakiew D, Euling S, Ho SM, Landolph J, Morrison H, Sonawane B, Shifflett T, Waters DJ, Timms B (2004). Human prostate cancer risk factors. Cancer 101(10 Suppl):2371-490.
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