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Contact Information:

Division of Basic Biomedical Sciences
Sanford School of Medicine of The University of South Dakota
414 E.Clark Street
Vermillion, SD 57069
phone: (605)-677-5254
fax: (605)-677-6381
biomed@usd.edu

Last Modified: 08/24/07

/biomed/images/faculty/ArmstrongStephen.jpg

   Stephen Armstrong, Ph.D. (University of Pennsylvania)

   Associate Professor
   Cardiovascular Biology / Biochemistry
   (605) 328-1300
   sarmstro@usd.edu 
   webpage (Opens a new window)

Education
B. Sci. Microbiology - University of Florida, Gainesville, FL
Ph.D., Microbiology - University of Pennsylvania, Philadelphia, PA

Experience
• 8/04 -present  Associate Professor, Cardiovascular Research Institute, University of South Dakota School of Medicine
• 6/04 -7-04    Assistant Professor, Cardiovascular Research Institute, University of South Dakota School of Medicine; Sioux Falls, SD
• 9/94-5/04 Assistant Professor  Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 3/91-8/93 Instructor, Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 9/89  - 2/91 Research Specialist, Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 3-86 -8/89 Post-doctoral Research Fellow, Department of Microbiology, James Quillen College of Medicine, East Tennessee State University, Johnson City, TN

Distinctions
Publications- 29
Book Chapters- 3
Grant Reviewer- American Heart Association- Southeast Affiliate 2003-2004

Awards
NIH-NHLBI Grant 1RO1 HL077713-01 "Myocardial Ischemic Activation of the Akt Pathway" 7/04 - 6/08.

Research Focus
Myocardial ischemia and the signal transduction pathways that mediate the endogenous cardio-protective mechanism- ischemic preconditioning. Specifically activation of the Akt/GSK-3 pathway during ischemia and the downstream substrates that are phosphorylated by this pathway.

Publications
Armstrong, SC. 2004. Protein kinase activation and myocardial ischemia/reperfusion injury. Cardiovasc Res 61: 427-436.

Armstrong SC, Latham CA, Ganote CE. 2003. An ischemic ß-dystroglycan degradation product: Correlation with irreversible injury in adult rabbit cardiomyocytes. Mol Cell Biochem  242:71-79.

Armstrong SC, Shivell LC, Latham CA, Ganote CE. 2001. Ischemic loss of sarcolemmal dystrophin and spectrin: Correlation with myocardial injury. J Mol Cell Cardiol  33:1165-1179.


 
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