Education
B. Sci. Microbiology - University of Florida, Gainesville, FL
Ph.D., Microbiology - University of Pennsylvania, Philadelphia, PA
Experience
• 8/04 -present Associate Professor, Cardiovascular Research Institute, University of South Dakota School of Medicine
• 6/04 -7-04 Assistant Professor, Cardiovascular Research Institute, University of South Dakota School of Medicine; Sioux Falls, SD
• 9/94-5/04 Assistant Professor Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 3/91-8/93 Instructor, Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 9/89 - 2/91 Research Specialist, Department of Pathology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN
• 3-86 -8/89 Post-doctoral Research Fellow, Department of Microbiology, James Quillen College of Medicine, East Tennessee State University, Johnson City, TN
Distinctions
Publications- 29
Book Chapters- 3
Grant Reviewer- American Heart Association- Southeast Affiliate 2003-2004
Awards
NIH-NHLBI Grant 1RO1 HL077713-01 "Myocardial Ischemic Activation of the Akt Pathway" 7/04 - 6/08.
Research Focus
Myocardial ischemia and the signal transduction pathways that mediate the endogenous cardio-protective mechanism- ischemic preconditioning. Specifically activation of the Akt/GSK-3 pathway during ischemia and the downstream substrates that are phosphorylated by this pathway.
Publications
Armstrong, SC. 2004. Protein kinase activation and myocardial ischemia/reperfusion injury. Cardiovasc Res 61: 427-436.
Armstrong SC, Latham CA, Ganote CE. 2003. An ischemic ß-dystroglycan degradation product: Correlation with irreversible injury in adult rabbit cardiomyocytes. Mol Cell Biochem 242:71-79.
Armstrong SC, Shivell LC, Latham CA, Ganote CE. 2001. Ischemic loss of sarcolemmal dystrophin and spectrin: Correlation with myocardial injury. J Mol Cell Cardiol 33:1165-1179.