Sanford School of Medicine Basic Biomedical Sciences

Alicia Goyeneche, Ph.D.

Alicia Goyeneche
Assistant Professor
Basic Biomedical Sciences, School of Medicine
UMS Lee Med/Sanford School of Medicine 242
Phone: 605-677-6833
Education:
  • Ph D, Reproductive Endocrinology, National University of San Luis,
  • BS, Biochemistry, National University of San Luis, 1989
  • BS, Chemistry, National University of San Luis, 1986
Publications:
  • Brandhagen, B. N., Tieszen, C. R., Ulmer, T. M., Tracy, M. S., Goyeneche, A., Telleria, C., (2013), Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics, BMC Cancer, vol. 13, iss. 35.
  • Telleria, C., Goyeneche, A., , (2012), Antiprogestins in ovarian cancer., Intech Open Access Publisher , vol. 11, pp. 207-230.
  • Tieszen, C., Goyeneche, A., Brandhagen, B., Ortbahn, C., Telleria, C., (2011), Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression. , BMC Cancer , iss. 11, p. 207.
  • Goyeneche, A., Seidel, E., Telleria, C., (2011), Growth inhibition induced by antiprogestins RU-38486, ORG-13710, and CDBG-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2, Investigational New Drugs.
  • Tieszen, C., Goyeneche, A., (2009), Growth inhibition properties of antiprogestin mifepristone in cancer cells. , BRIN Summer Research Forum.
  • Tieszen, C., Goyeneche, A., (2009), Growth inhibitory properties of mifepristone in reproductive- and non-reproductive system-related cancers. , Annual Graduate Student Research Forum, iss. 40.
  • Villavicencio, A., Goyeneche, A., Telleria, C., Bacallao, K., Gabler, F., Fuentes, A., Vega, M., (2009), Involvement of AKT, Ras and cell cycle regulators in the potential development of endometrial hyperplasia in women with polycystic ovarian syndrome, Gynecologic Oncology , iss. 115, pp. 102-107.
  • Freeburg, E., Goyeneche, A., Telleria, C., (2009), Mifepristone abrogates repopulation of ovarian cancer cells in between courses of cisplatin treatment. , International Journal of Oncology, iss. 34, pp. 743-755.
  • Freeburg, E., Goyeneche, A., Telleria, C., (2009), Resistance to cisplatin does not affect sensitivity of human ovarian cancer cell lines to mifepristone cytotoxicity. , Cancer Cell International , iss. 9, p. 4.
  • Freeburg, E., Goyeneche, A., (2009), Resistance to cisplatin does not affect sensitivity of human ovarian cancer cell lines to mifepristone. , AACR, iss. 809.
  • Goyeneche, A., Telleria, C., (2007), Mifepristone inhibits ovarian cancer cell growth in vitro and in vivo. , Clinical Cancer Research , iss. 13, pp. 3370-3379.
  • Goyeneche, A., Harmon, J., Telleria, C., (2006), Cell death induced by serum deprivation in luteal cells involves the intrinsic pathway of apoptosis., Reproduction , iss. 131, pp. 103-111.
  • Goyeneche, A., Telleria, C., (2005), Exogenous estradiol enhances apoptosis in regressing post-partum rat corpora lutea possibly mediated by prolactin. , Reproductive Biology and Endocrinology , iss. 3, p. 40.
  • Telleria, C., Goyeneche, A., Stocco, C., Gibori, G., (2004), . Involvement of nuclear factor kappa B in rat luteal function: potential roles as survival factor and inhibitor of 20alpha-hydroxysteroid dehydrogenase. , Journal of Molecular Endocrinology , iss. 32, pp. 365-383.
  • Goyeneche, A., Martinez, L., Deis, R., Gibori, G., Telleria, C., (2003), In-vivo hormonal environment leads to differential susceptibility of the corpus luteum to apoptosis in-vitro. , Biology of Reproduction , iss. 68, pp. 2322-2330.
  • Goyeneche, A., Deis, R., Gibori, G., Telleria, C., (2003), Progesterone promotes survival of the rat corpus , Biology of Reproduction , iss. 68, pp. 151-158.
  • Goyeneche, A., Calvo, V., Gibori, G., Telleria, C., (2002), Androstenedione interferes in luteal regression by inhibiting apoptosis and stimulating progesterone production., Biology of Reproduction, iss. 66, pp. 1540-1547.
  • Telleria, C., Goyeneche, A., Cavicchia, J., Stati, A., Deis, R., (2001), Apoptosis induced by antigestagen RU486 in rat corpus luteum of pregnancy. , Endocrine, iss. 15, pp. 147-155.
Presentations:
  • Goyeneche, A., Bell, M., Telleria, C. (2011, May). Primary ex-vivo culture of a huma mucinous adenocarcinoma of the ovary: a case report. Presented at the Second Annual Sanford Health-USD BBS Symposium, Sioux Falls, SD.
  • Goyeneche, A., Seidel, E. E., Telleria, C. (2010, May). Antiprogestins are cytostatic at pharmacological concentrations and lethal at supra-pharmacological concentrations to ovarian cancer cells. Presented at the FIrst Annual Sanford Health-USD BBS Symposium, Vermillion, SD.
  • Goyeneche, A. (2009, October). Presented at the Journal Club Presentation, University of South Dakota - BBS.