Sanford School of Medicine Basic Biomedical Sciences

Lisa Moore

Lisa Moore
Assistant Professor
Medicine: Basic Biomedical Sciences, Health Affairs
UMS Lee Med/Sanford School of Medicine 366
Phone: 605-677-5164
Bio:
In 1999, I earned my B.S. from the College of Charleston followed by my doctorate in 2005 from West Virginia University. I performed my postdoctoral fellowship at the Rocky Mountain Laboratories.
Teaching Interests:
I am interested in teaching sexually transmitted disease lectures to Medical Students, as well as leading graduate courses on microbial pathogenesis.
Research Interests:
I study how the obligate intracellular pathogen Chlamydia trachomatis acquires vital nutrients from the eukaryotic host cell. These studies require that I be on the cutting edge of cellular microbiology.
Education:
  • Post-doctoral Fellowship, Laboratory of Intracellular Parasites, NIH, NIAID, Rocky Mountain Laboratories, 2010
  • Ph D, Microbiology and Immunology, West Virginia University, 2005
  • BS, Biology, College of Charleston, 1999
Research:
  • Sloan Research Application in Chemistry, Alfred P. Sloan Foundation
Publications:
  • Kabeiseman, E. J., Cichos, K., Hackstadt, T., Lucas, A., Moore, L. R., (2013), VAMP4 and syntaxin 6 interactions at the chlamydial inclusion, Infection and Immunity, vol. 81, iss. 9, pp. 3326-3337.
  • Moore, L. R., (2012), Sphingolipid trafficking and purification in Chlamydia trachomatis-infected cells, John Wiley & Sons, Inc, vol. 27, pp. 11A.2.1-11A.2.19.
  • Bridge, D. R., Martin, K. H., Moore, L. R., Lee, W. M., Carroll, J. A., Rocha, C. L., Olson, J. C., (2012), Examining the role of actin-plasma membrane association in Pseudomonas aeruginosa infection and T3S translocation in migratory T24 epithelial cells, Infection and Immunity.
  • Moore, L. R., Mead, D. J., Dooley, C. A., Sager, J., Hackstadt, T., (2011), The trans-Golgi SNARE syntaxin 6 is recruited to the chlamydial inclusion membrane., Microbiology, vol. 157, pp. 830-838.
  • Bridge, D. R., Novotny, M. J., Moore, L. R., Olson, J. C., (2010), Role of host cell polarity and leading edge properties in Pseudomonas type III secretion., Microbiology, vol. 156, iss. 2, pp. 356-373.
  • Moore, L. R., Fischer, E. R., Mead, D. J., Hackstadt, T., (2008), The chlamydial inclusion preferentially intercepts basolaterally directed sphingomyelin-containing exocytic vacuoles, Traffic, vol. 9, pp. 2130-2140.
  • Moore, L. R., Olson, J. C., (2005), Characterization of an ExoS type III translocation resistant cell line, Infection and Immunity, vol. 73, pp. 638-643.
  • Rocha, C. L., Moore, L. R., Vincent, D. M., Olson, J. C., (2005), Examination of the coordinate effects of Pseudomonas ExoS on Rac1, Infection and Immunity, vol. 73, pp. 5458-5467.
  • Rocha, C. L., Coburn, J., Moore, L. R., Olson, J. C., (2004), Characterization of Pseudomonas aeruginosa exoenzyme S as a bifunctional enzyme in J774A.1 macrophages, Infection and Immunity, vol. 71, pp. 5296-5305.
  • Moore, L. R., Fraylick, J. E., Brandt, L. M., Vincent, T. S., Olson, J. C., (2003), Cell line differences in bacterially translocated ExoS ADP-ribosyltransferase substrate specificity, Microbiology, vol. 149, pp. 319-331.
  • Fraylick, J. E., Moore, L. R., Greene, D. M., Vincent, T. S., Olson, J. C., (2002), Eukaryotic cell determination of ExoS ADP-ribosyltransferase substrate specificity, Biochemical Biophysical Research Communications, vol. 291, pp. 91-100.
Presentations:
  • Lucas, A. L., Kabeiseman, E. J., Moore, L. R. (2013, October). Examination of trans-Golgi SNARE syntaxin 10 interactions at the chlamydial inclusion. Presented at the American Society of Microbiology North Central Branch Meeting, Brookings, SD.
  • Moore, L. R. (2013, September). Eukaryotic SNARE interactions at the chlamydial inclusion. Presented at the Faculty Seminar Series, Morgantown, WV.
  • Moore, L. R. (2013, April). VAMP4 targets syntaxin 6 to the chlamydial inclusion. Presented at the Microbiology General Seminar, Knoxville, TN.
  • Lucas, A. L., Moore, L. R. (2013, March). Examination of trans-Golgi SNARE syntaxin 10 interactions at the chlamydial inclusion.. Presented at the Chlamydia Basic Research Society 6th Meeting, San Antonio, TX.
  • Kabeiseman, E. J., Cichos, K. H., Moore, L. R. (2013, March). Interrogation of syntaxin 6 and VAMP4 interactions at the chlamydial inclusion.. Presented at the Chlamydia Basic Research Society 6th Meeting, San Antonio, TX.
  • Kabeiseman, E. J., Cichos, K. H., Moore, L. R. (2013, March). Localization of syntaxin 6 to the chlamydial inclusion requires the ygrl signal sequence and VAMP4.. Presented at the Chlamydia Basic Research Society 6th Meeting, San Antonio, TX.
  • Moore, L. R. (2012, April). Examining the role of syntaxin 6 in trafficking lipids to the chlamydial inclusion. Presented at the Glycolipid and Sphingolipid Biology, Il Ciocco Resort, Lucca (Barga), Italy.
  • Moore, L. R. (2012, March). The plasma membrane retrieval signal, YGRL, specifically targets proteins to the chlamydial inclusion.
  • Moore, L. R. (2012, February). The plasma membrane retrieval signal, YGRL, specifically targets proteins to the chlamydial inclusion.
  • Moore, L. R., McDowell, E., Cichos, K., Rinehart, C. (2011, September). The plasma membrane retrieval signal, ygrl, specifically targets proteins to the chlamydial inclusion.. Presented at the Microbial Pathogenesis and Host Response, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY.
  • Moore, L. R., Dooley, C. A., Mead, D. J., Sager, J., Hackstadt, T. (2011, March). Localization of trans-Golgi SNARE syntaxin 6 to the chlamydial inclusion.. Presented at the Chlamydia Basic Research Society, 5th Meeting, Redondo Beach, CA.