Sanford School of Medicine Basic Biomedical Sciences

Michael Chaussee, Ph.D.

Michael Chaussee
Associate Professor
Basic Biomedical Sciences, School of Medicine
UMS Lee Med/Sanford School of Medicine 339
Phone: 605-658-6380
Education:
  • Ph D, University of Oklahoma Health Sciences Center, 1995
  • BS, University of Minnesota, 1990
Publications:
  • Vukonich, M., Moline, H., Chaussee, M., Huntington, M., Case report: chorioamnionitis attributed to Streptococcus thoraltensis, South Dakota Medicine.
  • Klonoski, J. M., Hurtig, H. R., Juber, B. A., Schuneman, M. J., Bickett, T. E., Svendsen, J. M., Burum, B., Penfound, T. A., Sereda, G., Dale, J. B., Chaussee, M., Huber, V., (2014), Vaccination against the M protein of Streptococcus pyogenes prevents death after influenza virus: S. pyogenes super-infection., Vaccine, vol. 32, iss. 40, pp. 5241-9. (DOI: 10.1016/j.vaccine.2014.06.093)
  • Dmitriev, A., Chaussee, M., (2013), Dependence of Streptococcus pyogenes properties from the rgg gene transcriptional level, Medical Academic Journal, vol. 13, iss. 114-119 .
  • Chaussee, M., Anbalagan, S., (2013), Transcriptional regulation of a bacteriophage encoded extracellular DNase (Spd-3) by Rgg in Streptococcus pyogenes, Plos One, vol. 17, p. e61312.
  • McDowell, E., Callegari, E., Malke, H., Chaussee, M., (2012), CodY-mediated regulation of Streptococcus pyogenes exoproteins , BMC Microbiology.
  • Anbalagan, P., McShans, W. M., Dunman, P., Chaussee, M., (2012), Growth phase-dependent modulation of Rgg binding sites in Streptococcus pyogenes, Journal of Bacteriology.
  • Anbalagan, S., Dmitriev, A., McShan, W. M., Dunman, P. M., Chaussee, M., (2012), Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes., Journal of bacteriology, vol. 194, iss. 15, pp. 3961-71. (DOI: 10.1128/JB.06709-11)
  • Anbalagan, S., Dunman, P., McShan, W. M., Chaussee, M., (2011), Identification of Rgg binding sites in the Streptococcus pyogenes chromosome, Journal of Bacteriology, vol. 193, pp. 4933-4942.
  • Chaussee, M., Sandbulte, H., Schuneman, M. J., DePaula, F., Addengast, L., Schlenker, E., Huber, V., (2011), Inactivated and live, attenuated influenza vaccines protect mice against influenza:Streptococcus pyogenes super-infections, Vaccine.
  • Chaussee, M., (2010), Community-based intervention to manage an outbreak of methicillin-resistant Staphylococcus aureus skin infection, Journal of Correctional Health Care.
  • Dmitriev, A. V., Chaussee, M., (2010), The Streptococcus pyogenes proteome: maps, virulence factors and vaccine candidates., Future microbiology, vol. 5, iss. 10, pp. 1539-51. (DOI: 10.2217/fmb.10.116)
  • Elias, A. F., Chaussee, M., McDowell, E. J., Huntington, M. K., (2010), Community-based intervention to manage an outbreak of MRSA skin infections in a county jail., Journal of correctional health care : the official journal of the National Commission on Correctional Health Care, vol. 16, iss. 3, pp. 205-15. (DOI: 10.1177/1078345810366679)
  • Chaussee, M., , (2009), A naturally occurring Rgg variant in serotype M3 Streptococcus pyogenes does not activate speB expression due to altered specificity of DNA binding. , Infection and Immunity, iss. 77, pp. 5411-5417.
  • Chaussee, M., (2009), Escherichia coli O157:H7 NleH proteins bind the human ribosomal protein S3 to subvert NF-?B function. , PLOS Pathogens, vol. 5, iss. 12.
  • Chaussee, M., , (2009), NleH proteins bind the human ribosomal protein S3 to subvert NF-?B function. , PLOS Pathogens, vol. 5, iss. 12.
  • Gao, X., Wan, F., Mateo, K., Callegari, E., Wang, D., Deng, W., Puente, J., Li , F., Chaussee, M., Finlay, B. B., Lenardo, M. J., Hardwidge, P. R., (2009), Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function., PLoS pathogens, vol. 5, iss. 12, p. e1000708. (DOI: 10.1371/journal.ppat.1000708)
  • Dmitriev, A. V., McDowell, E. J., Chaussee, M., (2008), Inter- and intraserotypic variation in the Streptococcus pyogenes Rgg regulon., FEMS microbiology letters, vol. 284, iss. 1, pp. 43-51. (DOI: 10.1111/j.1574-6968.2008.01171.x)
  • Chaussee, M., Dmitriev, A. V., Callegari, E. A., Chaussee, M., (2008), Growth phase-associated changes in the transcriptome and proteome of Streptococcus pyogenes., Archives of microbiology, vol. 189, iss. 1, pp. 27-41. (DOI: 10.1007/s00203-007-0290-1)
  • Chaussee, M., McDowell, E. J., Chaussee, M., (2008), Proteomic analysis of proteins secreted by Streptococcus pyogenes., Methods in molecular biology (Clifton, N.J.), vol. 431, pp. 15-24.
  • Reid, S. D., Chaussee, M., Doern, C. D., Chaussee, M., Montgomery, A. G., Sturdevant, D. E., Musser, J. M., (2006), Inactivation of the group A Streptococcus regulator srv results in chromosome wide reduction of transcript levels, and changes in extracellular levels of Sic and SpeB., FEMS immunology and medical microbiology, vol. 48, iss. 2, pp. 283-92. (DOI: 10.1111/j.1574-695X.2006.00150.x)
  • Chaussee, M., McDowell, E. J., Rieck, L. D., Callegari, E. A., Chaussee, M., (2006), Proteomic analysis of a penicillin-tolerant rgg mutant strain of Streptococcus pyogenes., The Journal of antimicrobial chemotherapy, vol. 58, iss. 4, pp. 752-9. (DOI: 10.1093/jac/dkl319)
  • Dmitriev, A. V., McDowell, E. J., Kappeler, K. V., Chaussee, M., Rieck, L. D., Chaussee, M., (2006), The Rgg regulator of Streptococcus pyogenes influences utilization of nonglucose carbohydrates, prophage induction, and expression of the NAD-glycohydrolase virulence operon., Journal of bacteriology, vol. 188, iss. 20, pp. 7230-41. (DOI: 10.1128/JB.00877-06)
  • Wood, D. N., Chaussee, M., Chaussee, M., Buttaro, B. A., (2005), Persistence of Streptococcus pyogenes in stationary-phase cultures., Journal of bacteriology, vol. 187, iss. 10, pp. 3319-28. (DOI: 10.1128/JB.187.10.3319-3328.2005)
  • Chaussee, M., Callegari, E. A., Chaussee, M., (2004), Rgg regulates growth phase-dependent expression of proteins associated with secondary metabolism and stress in Streptococcus pyogenes., Journal of bacteriology, vol. 186, iss. 21, pp. 7091-9. (DOI: 10.1128/JB.186.21.7091-7099.2004)
  • Chaussee, M., Somerville, G. A., Reitzer, L., Musser, J. M., (2003), Rgg coordinates virulence factor synthesis and metabolism in Streptococcus pyogenes., Journal of bacteriology, vol. 185, iss. 20, pp. 6016-24.
  • Somerville, G. A., Chaussee, M., Morgan, C. I., Fitzgerald, J. R., Dorward, D. W., Reitzer, L. J., Musser, J. M., (2002), Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival., Infection and immunity, vol. 70, iss. 11, pp. 6373-82.
  • Smoot, J. C., Barbian, K. D., Van Gompel, J. J., Smoot, L. M., Chaussee, M., Sylva, G. L., Sturdevant, D. E., Ricklefs, S. M., Porcella, S. F., Parkins, L. D., Beres, S. B., Campbell, D. S., Smith, T. M., Zhang, Q., Kapur, V., Daly, J. A., Veasy, L. G., Musser, J. M., (2002), Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks., Proceedings of the National Academy of Sciences of the United States of America, vol. 99, iss. 7, pp. 4668-73. (DOI: 10.1073/pnas.062526099)
  • Chaussee, M., Sylva, G. L., Sturdevant, D. E., Smoot, L. M., Graham, M. R., Watson, R. O., Musser, J. M., (2002), Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes., Infection and immunity, vol. 70, iss. 2, pp. 762-70.
  • Chaussee, M., Watson, R. O., Smoot, J. C., Musser, J. M., (2001), Identification of Rgg-regulated exoproteins of Streptococcus pyogenes., Infection and immunity, vol. 69, iss. 2, pp. 822-31. (DOI: 10.1128/IAI.69.2.822-831.2001)
  • McCourt, M. E., Freeman, P., Tahmahkera-Stevens, C., Chaussee, M., (2001), The influence of unimanual response on pseudoneglect magnitude., Brain and cognition, vol. 45, iss. 1, pp. 52-63. (DOI: 10.1006/brcg.2000.1255)
  • Chaussee, M., Cole, R. L., van Putten, J. P., (2000), Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cells., Infection and immunity, vol. 68, iss. 6, pp. 3226-32.
  • Chaussee, M., Ajdic, D., Ferretti, J. J., (1999), The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production., Infection and immunity, vol. 67, iss. 4, pp. 1715-22.
  • Chaussee, M., Wilson, J., Hill, S. A., (1999), Characterization of the recD gene of Neisseria gonorrhoeae MS11 and the effect of recD inactivation on pilin variation and DNA transformation., Microbiology (Reading, England), vol. 145 ( Pt 2), pp. 389-400.
  • Chaussee, M., Hill, S. A., (1998), Formation of single-stranded DNA during DNA transformation of Neisseria gonorrhoeae., Journal of bacteriology, vol. 180, iss. 19, pp. 5117-22.
  • Chaussee, M., Phillips, E. R., Ferretti, J. J., (1997), Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion., Infection and immunity, vol. 65, iss. 5, pp. 1956-9.
  • Chaussee, M., Liu, J., Stevens, D. L., Ferretti, J. J., (1997), Effects of environmental factors on streptococcal erythrogenic toxin A (SPE A) production by Streptococcus pyogenes., Advances in experimental medicine and biology, vol. 418, pp. 551-4.
  • Chaussee, M., Liu, J., Stevens, D. L., Ferretti, J. J., (1996), Genetic and phenotypic diversity among isolates of Streptococcus pyogenes from invasive infections., The Journal of infectious diseases, vol. 173, iss. 4, pp. 901-8.
  • Gross, M. D., Hays, R., Gapstur, S. M., Chaussee, M., Potter, J. D., (1994), Evidence for the formation of multiple types of acetaldehyde-haemoglobin adducts., Alcohol and alcoholism (Oxford, Oxfordshire), vol. 29, iss. 1, pp. 31-41.
  • Chaussee, M., Gerlach, D., Yu, C. E., Ferretti, J. J., (1993), Inactivation of the streptococcal erythrogenic toxin B gene (speB) in Streptococcus pyogenes., Infection and immunity, vol. 61, iss. 9, pp. 3719-23.
Presentations:
  • Dmietriev, A. V., Zutkis, A. S., Anbalagan, S., Milman, B. L., Chaussee, M. (2014, November). RGG2-CONTROLLED GENE EXPRESSION IN STREPTOCOCCUS PYOGENES. Presented at the Lancefield International Conference of Streptococci and Streptococcal Diseases, Buenos Aires, Argentina.
  • Chaussee, M. (2014, March). Bacterial superinfections: the deadly side of influenza.
  • Bickett, T., Klonoski, J., Mottishaw, W., Dale, J., Chaussee, M., Sereda, G., Huber, V. (2013, June). Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the It’s All About Science Festival, Sioux Falls, SD.
  • Bickett, T., Klonoski, J., Mottishaw, W., Dale, J., Chaussee, M., Sereda, G., Huber, V. (2013, May). Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the Sanford/USD Research Symposium, Sioux Falls, SD.
  • Bickett, T., Klonoski, J., Mottishaw, W., Dale, J., Chaussee, M., Sereda, G., Huber, V. (2013, May). Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the Biomaterials Day, Sioux Falls, SD.
  • Watson, T., Klonoski, J., Chaussee, M., Huber, V. (2013, April). A time course study of influenza A and Streptoccus pyogenes super infections in a mouse model. Presented at the Ideafest, Vermillion, SD.
  • Bickett, T., Klonoski, J., Mottishaw, W., Dale, J., Chaussee, M., Sereda, G., Huber, V. (2013, April). Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the Ideafest, Vermillion, SD.
  • Bickett, T., Klonoski, J., Mottishaw, W., Dale, J., Chaussee, M., Sereda, G., Huber, V. (2012, August). Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the USD Undergraduate Research Poster Presentation, Vermillion, SD.
  • Chaussee, M. (2011, September). Presented at the LANCEFIELD INTERNATIONAL MEETING, ITALY.
  • Anbalagan, S., Chaussee, M. (2011, July). Rgg binding sites vary in a growth phase-dependent manner. Presented at the Mid-West Gram-Positive Pathogenesis Consortiums Meeting, Nebraska City, NE.
  • Chaussee, M. (2011, March). Functional Genomics:  A solution to Streptococcal Disease in the 21st Century?. Presented at the The Joseph J. Ferretti Symposium: Confronting 21st Century Challenges in Infectious Disease, Oklahoma City, OK.
  • Chaussee, M. (2009, September). Mapping regulatory networks in the flesh-eating bacterium Streptococcus pyogenes. Presented at the 8th Great Plains Infectious Disease Meeting, Kansas City, KA.