Sanford School of Medicine Basic Biomedical Sciences

Pasquale Manzerra, Ph.D.

Pat Manzerra
Assistant Professor
Basic Biomedical Sciences, School of Medicine
UMS Lee Med/Sanford School of Medicine 246
Phone: 605-677-6882
Teaching Interests:
Medical Biochemistry; Undergraduate Biochemistry; Molecular Biology
Research Interests:
Neuronal Injury- Stroke, TBI and PTSD
Education:
  • Ph D, Department of Zoology, University of Toronto, 1997
  • BS, Division of Life Sciences, University of Toronto, 1989
Publications:
  • Paulson, A., Prasad, M. S., Henke-Thuringer, A. J., Manzerra, P., Transcriptional regulation of cadherins in neural development, Cell Adhesion and Migration, vol. 8, iss. 1.
  • Meyer, D., Davies, D., Barr, J., Manzerra, P., Forster, G., (2012), Mild Traumatic Brain Injury in the Rat Alters Neuronal Number in the Limbic System and Increases Conditioned Fear and Anxiety-like Behaviors., Experimental Neurology, vol. 235, pp. 574-87.
  • Carlisle, H. J., Manzerra, P., Marcora, E., Kennedy, M. B., (2008), SynGAP regulates steady-state activity-dependent phosphorylation of cofilin., J. Neurosci. , vol. 28, pp. 13673-13683.
  • Oh, J., Manzerra, P., Kennedy, M. B., (2004), Regulation of the neuron-specific ras GTPase-activating protein, syngap, by Ca2+/calmodulin-dependent protein kinase II. , JBC, vol. 279, pp. 17980-17988.
Awards and Honors:
  • Class of 1958 Basic Science Faculty Award, SSOM Alumni Relations Council, 2014
  • Class of 1958 Basic Science Faculty Award, SSOM Alumni Relations Council, 2014
  • Ontario Graduate Scholarship, Province of Ontario, Canada, 1993
  • University of Toronto Open Fellowship, University of Toronto, 1992
  • Ontario Graduate Scholarship, Province of Ontario, Canada, 1991
  • Ontario Graduate Scholarship, Province of Ontario, Canada, 1990
  • University of Toronto Open Fellowship, University of Toronto, 1989
Presentations:
  • Davies, D., Meyer, D., Barr, J., Manzerra, P., Forster, G. (2012). Effects of mild traumatic brain injury on limbic system and anxiety states. Presented at the School of Health Sciences Research Conference.
  • Olson, D. M., Meyer, D. L., Scholl, J. L., Watt, M., Manzerra, P., Renner, K., Forster, G. (2012, October). Effects of Mild Traumatic Brain Injury and Psychosocial Stress on Limbic Monoamines and Anxiety-like Behaviors.. Presented at the Society for Neuroscience Meeting, New Orleans, LA.
  • Davies, D., Meyer, D., Barr, J., Manzerra, P., Forster, G. (2012, May). Effects of mild traumatic brain injury on limbic system and anxiety states. Presented at the Sanford-USD Research Symposium, Vermillion.
  • Meyer, D. L., Davies, D., Barr, J. L., Manzerra, P., Forster, G. L. (2010, November). Neuronal loss within the limbic system in a rat model of closed mild traumatic brain injury. Presented at the Society for Neuroscience Meeting, San Diego, CA.
  • Manzerra, P. (2009, September). Synaptic Ras GTPase activating protein (SynGAP) regulates N-methyl-D-aspartate receptor (NMDAR)-mediated excitotoxicity via P38 MAPK activation.. Presented at the Research Frontiers in Brain Functioning and Disorders. , Ponca, NE.