Sanford School of Medicine Basic Biomedical Sciences

Yi-Fan Li, Ph.D.

Yi-Fan Li
Associate Professor
Medicine: Basic Biomedical Sciences, Health Affairs
UMS Lee Med/Sanford School of Medicine 145
Phone: 605-677-5204
Teaching Interests:
Medical Physiology
Research Interests:
Neuroregulation of Cardiovascular function
Education:
  • Ph D, Physiology, Beijing Medical University, 1996
  • MS, Physiology, Anhui College of Chinese Medicine, 1988
  • MD, Medicine, Chengde Medical College, 1981
Publications:
  • Tian, Z., Zheng, H., Li, J., Li, Y., Su, H., Wang, X., (2012), Genetically Induced Moderate Inhibition of the Proteasome in Cardiomyocytes Exacerbates Myocardial Ischemia-Reperfusion Injury in Mice, Circulation Research, vol. 111, iss. 5, pp. 532-542.
  • Sharma, N. M., Zheng, H., Li, Y., Patel, K. P., (2012), Nitric oxide inhibits the expression of AT1 receptors in neurons, Am J Physiol Cell Physiol, vol. 302, iss. 8, pp. C1162-73.
  • Zheng, H., Liu, X., Li, Y., Sharma, N. M., Patel, K. P., (2011), Gene Transfer of Neuronal Nitric Oxide Synthase to the Paraventricular Nucleus Reduces the Enhanced Glutamatergic Tone in Rats With Chronic Heart Failure, Hypertension, vol. 58, pp. 966-973.
  • Sharma, N. M., Zheng, H., Mehta, P. P., Li, Y., Patel, K. P., (2011), Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure:role for CAPON and Ang II , Cardiovascular Research, vol. 92, pp. 348-357.
  • Li, Y., Wang, X., (2011), The Role of the proteasome in heart disease, Biochim Biophys Acta - Gene Regulatory Mechanisms , vol. 1809, iss. 2, pp. 141-149.
  • Li, Y., (2010), Cytisine induces autonomic cardiovascular responses via activations of different nicotinic receptors., Autonomic Neuroscience: Basic and Clinical , vol. 154, pp. 14-19.
  • Li, Y., LaCroix, C., Freeling, J., (2009), Specific subtypes of nicotinic cholinergic receptors involved in sympathetic and parasympathetic cardiovascular responses.
  • Zheng, H., Li, Y., (2009), Enhanced angiotensin-mediated excitation of renal sympathetic nerve activity within the paraventricular nucleus of anesthetized rats with heart failure., Am J Physiol Regul Integr Comp Physiol, iss. 297, pp. 1364-1374.
  • Li, Y., (2009), Specific subtypes of nicotinic cholinergic receptors involved in sympathetic and parasympathetic cardiovascular responses., Neurosci Lett, iss. 462, pp. 20-23.
Presentations:
  • Solanki, R., Li, Y. (2012, December). Regulation of Norepinephrine Transporter (NET): A Potential Role of Ubiquitination. Presented at the BBS graduate seminar, Vermillion.
  • Solanki, R., Sample, A., Li, Y. (2012, October). UBIQUITIN AND NOREPINEPHRINE TRANSPORTER: A PRELIMINARY STUDY. Presented at the Nebraska Physiological Society Conference, Wayne State College, Wayne, NE.
  • Li, Y. (2012, April). Ubiquitination of Vesicular Acetylcholine Transporter. Presented at the Experimental Biology 2012, San Diego, CA.
  • Freeling, J., Li, Y. (2011, October). Attenuated Parasympathetic Nervous System Control of the Heart in the Aging Mouse. Presented at the NPS-IPS joint annual conference, Des Moines, IA.
  • Li, Y. (2011, May). Ubiquitin C-terminal Hydrolase L1 and Parasympathetic Cholinergic Function. Presented at the USD PQCD symposium, Vermillion.
  • Li, Y., Grandi, M., Freeling, J. (2011, April). Effect of Stimulation of a1 Adrenergic Receptors on Heart Rate . Presented at the Experimental Biology, Washington DC.
  • Freeling, J., Li, Y. (2011, April). The Parasympathetic Nervous System and the Aging Heart. Presented at the USD IdeaFest 2011, Vermillion.
  • Freeling, J., LaCroix, C., Grandi, M., Li, Y. (2010, September). Varenicline Induces Acetylcholine-dependent Bradycardic. Presented at the NPS annual conference, Omaha, NE.
  • Grandi, M., LaCroix, C., Freeling, J., Li, Y. (2010, July). Mouse Atrial Preparation and Response to Varenicline. Presented at the SD BRIN/Discover Poster Session, Vermillion.
  • Schiernbeck, C., Hutchinson, K., Freeling, J., Li, Y. (2010, July). Cholinergic Elements in Two Neuronal Cell Lines. Presented at the SD BRIN/U Discover Poster Session, Vermillion.
  • LaCroix, C., Freeling, J., Li, Y. (2010, April). Bradycardic response induced by stimulation of alpha4beta2 nicotinic receptors. Presented at the Experimental Biology, Anaheim, CA.
  • Freeling, J., LaCroix, C., Li, Y. (2010, April). Nicotinic a4ß2 Receptors Modulate Parasympathetic Regulation of the Heart. Presented at the USD IdeaFest 2010, Vermillion.