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Contact Information:

Center for Neural Mechanisms of Adaptive Behavior
414 East Clark Street
School of Medicine of The University of South Dakota
Vermillion, SD 57069
phone: 605-677-5140
fax: 605-677-6381
jkeifer@usd.edu

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Last Modified: 06/27/06

center for biomedical research excellence (COBRE)
on neural mechanisms of adaptive behavior

The Neuroscience Group at the University of South Dakota was awarded an $8 million research grant in 2000 from the National Institutes of Health, National Center for Research Resources, to establish a Center
of Biomedical Research Excellence (COBRE)  in the area
of Neural Mechanisms of Adaptive Behavior.  This grant was renewed for $9 million until 2010.  During the five year term of this grant, the Neuroscience Group, which is comprised primarily of School of Medicine and USD Department of Biology researchers, will be working on several interrelated research projects which are designed to address the major focus of the Center.  The main theme of our Center is to study the structural reorganization of neural pathways that results in adaptive behaviors in response to novel experiences or disease states.  Functional reorganization of neural circuits is fundamental to processes that occur during learning and memory, development, and in the central nervous system's response to stress and anxiety states or injury such as occurs during stroke or Alzheimer's disease.

Five main research projectsare sponsored by the Center.

The Center is composed of 14 faculty members and 26 students, postdocs and support staff.  For a list of the Neuroscience Group faculty and their research interests, click on faculty.

Core facilities include a Biological Imaging Core Facility housed within the School of Medicine.  This imaging facility is equipped primarily with an Olympus FluoView 500 Laser Scanning Confocal Microscope.  The confocal microscope has three laser lines for simultaneous imaging of multiple fluophores.  The facility also houses computers for image analysis including deconvolution and is staffed by a full-time technician.

For more information, please contact: Joyce Keifer, Ph.D., Neuroscience Group, Division of Basic Biomedical Sciences, School of Medicine of The University of South Dakota, Vermillion, SD, 57069. phone: (605) 677-5140; E-mail: jkeifer@usd.edu