The University of South Dakota

 Research Centers at the U create a critical mass of researchers, resources, and multi-disciplinary expertise to advance the boundaries of knowledge in a wide range of study. A partial list includes.

• South Dakota Small Business Development Center  provides resources, consultation, and support for emerging South Dakota businesses.  Through a network of six offices across the state and 1100 SBDC offices around the country, we provide professional, confidential and no-cost business consulting services, including one-on-one counseling and training, to individuals starting a business or looking for ways to improve an existing business. Since 1985, the South Dakota SBDC has helped clients obtain more than $651 million in financing, creating or preserving more than 12,014 jobs within the state. 
   
• The Center for Research and Development of Light-Activated Materials (CRDLM) is led by a diverse team of research scientists at the University of South Dakota, South Dakota State University, and the Avera Research Institute. The development of the CRDLAM was made possible by a grant awarded from the State of South Dakota through the Governor's 2010 Research Initiative.
  
• The Center for Rural Health Improvement was created to improve the health of South Dakotas through participatory community-based projects which target the major health needs in those communities. The Center emphasizes epidemiology and health services research with a major focus on health care access, disease prevention, and improved health outcomes.
  
• The Center for Ultra-low Background Experiments at DUSEL (CUBED) is designated a South Dakota Governor's 2010 Research Center.  CUBED was created to integrate with research initiatives planned at Sanford Underground Lab and at the Deep Underground Science and Engineering Laboratory (DUSEL), a national lab under development at the former Homestake gold mine in Lead, South Dakota.
  
• Disaster Mental Health Institute researchers work to promote, develop, and apply innovative practices and research in the field of disaster mental health. The Institute was founded in 1993 and was designated a South Dakota Board of Regents Center of Excellence in 1997.
  
• The Government Research Bureau (GRB) conducts applied research in the fields of public policy and public administration. The GRB's research and training focuses on leadership development, strategic planning for governments, non-profits, and businesses; data collection, analysis, and database development for governments and businesses; citizen and customer satisfaction assessment; and criminal justice research.  
  
• The Institute of American Indian Studies conducts research and policy development on tribal governance and issues in contemporary American Indian society. The Institute also develops, coordinates and funds interdisciplinary research projects, sustains relations with tribes and tribal colleges, advises on tribal relations and culture, issues publications, administers several endowments supportive of Native American education and student life, and hosts numerous lectures and conferences on topical Native American questions.
  
• The Missouri River Institute develops and promotes research, education, and public awareness related to the natural and cultural resources of the Missouri River basin. The institute's work is crucial, as the Missouri River system faces increasing demand on its resources.
  
• The Center for Biomedical Research Excellence (COBRE) on Neural Mechanisms of Adaptive Behavior studies the structural reorganization of neural pathways that results in adaptive behaviors in response to novel experiences or disease states.
  
• The U is the lead site for the South Dakota Biomedical Research Infrastructure Network (BRIN). We collaborate with project partners at seven sister sites in South Dakota to conduct research funded by the National Center for Research Resources, under the Institutional Development Award (IDeA) Program of the National Institutes of Health.    
  
• The USD Department of Chemistry coordinates the Northern Plains Undergraduate Research Center (NPURC), collaboration engaging eight regional colleges and universities to transform undergraduate research in chemistry.  NPURC provides a range of technical support and analytical services for researchers along with high-quality research experiences to first and second year undergraduates and research opportunities for more advanced undergrads and high school teachers.