David Hawkinson

David Hawkinson

Associate Professor

CHEMISTRY

Churchill-Haines Labs 115

Phone: (605) 677-5487

Email: David.Hawkinson@usd.edu

Teaching Interests:

Organic Chemistry: Physical Organic, Bioorganic, and Spectroscopy


Research Interests:

Organic Reaction Mechanisms, Bioorganic Chemistry


Education:

  • Ph D, Organic Chemistry, Northern Illinois University, 1988
  • BA, Chemistry, Augustana College, 1983

Grants:

  • REU Site: The Northern Plains REU Site - Serving the Needs of Regional Tribal Colleges and Local Primarily Undergraduate Institutions, National Science Foundation. Grant Role: Principal. (2011 - 2014)
  • Integration of NMR Spectroscopy Across the Chemistry Curricula at the University of South DakotaRole - Co-investigator, National Science Foundation. Grant Role: Co-Principal. (2003 - 2006)
  • Computer Upgrade and Networking of Multi-User Spectroscopic Instrumentation, NSF CRIF. Grant Role: Co-Principal. (1997 - 1998)
  • Determination of the Aqueous Acidities of Carbonyl Compounds, University of South Dakota Office of Research. Grant Role: Principal. (1993 - 1994)
  • Incorporating Fourier Transform Nuclear Magnetic Resonance Spectroscopy in the Undergraduate Laboratory Curriculum, University of South Dakota Faculty Development Grant. Grant Role: Co-Principal. (1993 - 1994)

Publications:

Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.

  • Hawkinson, David, and Ying, Wang. Relative Stabilities of Exocyclic, s-trans and Endocyclic, s-cis Dienolates: Enolization of 1-Decalenone, 3592-3595. Vol. 72. Journal of Organic Chemistry, 2007. (DOI: 10.1021/jo070068y)
  • Thornburg, Lora D., Henot, Frederic, Bash, Diarmad P., Hawkinson, David, Bartle, Shawn D., and Pollack, Ralph M.. Electrophilic Assistance by Asp-99 of 3-Oxo-?5-steroid Isomerase, 10499-10506. Vol. 37. Biochemistry, 1998. (DOI: 10.1021/bi980099a)
  • Hawkinson, David, Feiock, Jeffrey M., Nevy, John B., and Wu, Yue-Zhong. Enolization and Hydrolysis of 7-Nitroisochroman-3-one: Generation of a Relatively Stable Lactone Enolate, 5345-5349. Vol. 63. Journal of Organic Chemistry, 1998. (DOI: 10.1021/jo980032t)
  • Nevy, John B., Hawkinson, David, Blotny, Grzegorz, Yao, Xudong, and Pollack, Ralph M.. Transition State Imbalance in the Deprotonation of Substituted 2-Tetralones by Hydroxide Ion, 12722-12726. Vol. 119. Journal of the American Chemical Society, 1997. (DOI: 10.1021/ja972600c)
  • Zawrotny, Michael E., Hawkinson, David, Blotny, Grzegorz, and Pollack, Ralph M.. Mechanism of Proton Transfer in the Isomerization of 5-Androstene-3,17-dione by 3-Oxo-?5-steroid Isomerase and its D38E Mutant, 6438-6442. Vol. 35. Biochemistry, 1996. (DOI: 10.1021/bi953025x)
  • Hawkinson, David, Pollack, Ralph M., and Ambulos Jr., Nicholas P.. Evaluation of the Internal Equilibrium Constant for 3-Oxo-?5-steroid Isomerase Using the D38E and D38N Mutants: The Energetic Basis for Catalysis, 12172-12183. Vol. 33. Biochemistry, 1994. (DOI: 10.1021/bi00206a021)
  • Hawkinson, David, and Pollack, Ralph M.. Is a Proton Relay Involved in the Mechanism of 3-Oxo-?5-steroid Isomerase?, 694-698. Vol. 32. Biochemistry, 1993. (DOI: 10.1021/bi00053a038)
  • Hawkinson, David, Eames, Teresa C., and Pollack, Ralph M.. Energetics of 3-Oxo-?5-Steroid Isomerase: Source of the Catalytic Power of the Enzyme, 10849-10858. Vol. 30. Biochemistry, 1991. (DOI: 10.1021/bi00109a007)
  • Hawkinson, David, Eames, Teresa C., and Pollack, Ralph M.. Kinetic Competence of an Externally Generated Dienol Intermediate with Steroid Isomerase, 6956-6964. Vol. 30. Biochemistry, 1991. (DOI: 10.1021/bi00242a021)
  • Eames, Teresa C., Hawkinson, David, and Pollack, Ralph M.. Direct Determination of the Partitioning of an Enzyme-Bound Intermediate, 1996-1998. Vol. 112. Journal of the American Chemical Society, 1990. (DOI: 10.1021/ja00161a054)
  • Kevill, Dennis N., Adolf, Horst R., Wang, An, Hawkinson, David, and D'Souza, Malcom J.. Perchlorate Esters. Part 9. Correlation of the Rates of Solvolysis of Methyl Perchlorate, 2023-2028. Journal of the Chemical Society, Perkin Transactions II, 1990. (DOI: 10,1039/P29900002023)
  • Kevill, Dennis N., and Hawkinson, David. Solvolysis of 1-Adamantyl Nitrate. A YONO2 Scale and Product Partitioning in Aqueous Ethanol, 5394-5399. Vol. 55. Journal of Organic Chemistry, 1990. (DOI: 10.1021/jo00306a018)
  • Kevill, Dennis N., and Hawkinson, David. Correlation of the Rates of Solvolysis of 2-Adamantyl 2,2,2-Trifluoroethanesulfonate: A YOTr Scale, 154-158. Vol. 54. Journal of Organic Chemistry, 1989. (DOI: 10.1021/jo000262a035)
  • Hawkinson, David, and Kevill, Dennis N.. Studies of the Solvolysis of 2-Adamantyl Pentafluorobenzenesulfonate: A YPFBS Scale, 3857-3860 . Vol. 53. Journal of Organic Chemistry, 1988. (DOI: 10.1021/jo00251a039)
  • Kevill, Dennis N., Rissmann, Thomas J., and Hawkinson, David. Preparation of Boron-Carbon Compositions by Chemical Vapor Deposition. In Proceedings of the Fourth Working Group Meeting on Thermoelectrics, Section III: Boron Carbides and Boron-Rich Borides. Vol. 1985. Pasadena, CA: Jet Propulsion Laboratory/NASA, 1985.

Awards and Honors:

  • Doctoral Research Award, Graduate School - Northern Illinois University, 1987

Presentations:

  • Hawkinson, David. Reactivity of Esters with Anilinomagnesium Halides. Presented at the 47th Midwest Regional Meeting of the American Chemical Society, Omaha, NE. (October 24, 2012)
  • Hawkinson, David, Furness, Amanda. Studies of the Bodroux Reaction in Tetrahydrofuran. Presented at the 46th Midwest-39th Great Lakes Joint Regional Meeting of the American Chemical Society, Saint Louis, MO. (October 20, 2011)
  • Hawkinson, David, May, Stanley, Engebretson, Daniel, Burum, Brandon, Baride, Avavind. Two?photon uncaging of coumarin from cinnamate?coated CdSe quantum dots as a model drug delivery system.. Presented at the 45th Midwest Regional Meeting of the American Chemical Society, Wichita, KS. (October 19, 2010)