Michael Chaussee

Michael Chaussee

Associate Professor


Lee Medicine & Science Hall 339

Phone: (605) 658-6380

Email: Michael.Chaussee@usd.edu


  • Ph D, University of Oklahoma Health Sciences Center, 1995
  • BS, University of Minnesota, 1990


  • Role of influenza-induced prothrombosis in Streptococcus pyogenes superinfections, NIH. Grant Role: Principal. (2012 - 2015)


Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.

  • Dmitriev, Alexander V., Chaussee, Michael S., and Kalinina, O V.. Rgg-like transcriptional proteins in Streptococcus spp, 303-314. Iss. 5. Russian Journal of Infection and Immunity (Infektsiya i Immunitet), 2015.
  • Vukonich, M, Moline, H, Chaussee, Michael, and Huntington, M. Case report: chorioamnionitis attributed to Streptococcus thoraltensis, 98-9. Vol. 68. Sioux Falls, SD: South Dakota Medicine, 2015.
  • Klonoski, J M., Hurtig, H R., Juber, B A., Schuneman, M J., Bickett, T E., Svendsen, J M., Burum, B, Penfound, T A., Sereda, Grigoriy, Dale, J B., Chaussee, Michael, and Huber, Victor. Vaccination against the M protein of Streptococcus pyogenes prevents death after influenza virus: S. pyogenes super-infection., 5241-9. Vol. 32, Iss. 40. Vaccine, 2014. (DOI: 10.1016/j.vaccine.2014.06.093)
  • Dmitriev, Alexander, and Chaussee, Michael. Dependence of Streptococcus pyogenes properties from the rgg gene transcriptional level. Vol. 13, Iss. 114-119 . Medical Academic Journal, 2013.
  • Chaussee, Michael, and Anbalagan, Srivishnupriya. Transcriptional regulation of a bacteriophage encoded extracellular DNase (Spd-3) by Rgg in Streptococcus pyogenes, e61312. Vol. 17. Plos One, 2013.
  • Anbalagan, Priay, McShans, William M., Dunman, Paul, and Chaussee, Michael. Growth phase-dependent modulation of Rgg binding sites in Streptococcus pyogenes. Journal of Bacteriology, 2012.
  • Anbalagan, S, Dmitriev, A, McShan, W M., Dunman, P M., and Chaussee, Michael. Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes., 3961-71. Vol. 194, Iss. 15. Journal of bacteriology, 2012. (DOI: 10.1128/JB.06709-11)
  • McDowell, Emily, Callegari, Eduardo, Malke, Horst, and Chaussee, Michael. CodY-mediated regulation of Streptococcus pyogenes exoproteins. BMC Microbiology, 2012.
  • Anbalagan, Srivishnupriya, Dunman, Paul, McShan, William M., and Chaussee, Michael. Identification of Rgg binding sites in the Streptococcus pyogenes chromosome, 4933-4942. Vol. 193. Journal of Bacteriology, 2011.
  • Chaussee, Michael, Sandbulte, Heather, Schuneman, Margaret J., DePaula, Frank, Addengast, Leslie, Schlenker, Evelyn, and Huber, Victor. Inactivated and live, attenuated influenza vaccines protect mice against influenza:Streptococcus pyogenes super-infections. Vaccine, 2011.
  • Dmitriev, A V., and Chaussee, Michael. The Streptococcus pyogenes proteome: maps, virulence factors and vaccine candidates., 1539-51. Vol. 5, Iss. 10. Future microbiology, 2010. (DOI: 10.2217/fmb.10.116)
  • Elias, A F., Chaussee, Michael, McDowell, E J., and Huntington, M K.. Community-based intervention to manage an outbreak of MRSA skin infections in a county jail., 205-15. Vol. 16, Iss. 3. Journal of correctional health care : the official journal of the National Commission on Correctional Health Care, 2010. (DOI: 10.1177/1078345810366679)
  • Chaussee, Michael. Community-based intervention to manage an outbreak of methicillin-resistant Staphylococcus aureus skin infection. Journal of Correctional Health Care, 2010.
  • Gao, X, Wan, F, Mateo, K, Callegari, E, Wang, D, Deng, W, Puente, J, Li, F, Chaussee, Michael, Finlay, B B., Lenardo, M J., and Hardwidge, P R.. Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function., e1000708. Vol. 5, Iss. 12. PLoS pathogens, 2009. (DOI: 10.1371/journal.ppat.1000708)
  • Chaussee, Michael, and . A naturally occurring Rgg variant in serotype M3 Streptococcus pyogenes does not activate speB expression due to altered specificity of DNA binding., 5411-5417. Iss. 77. Infection and Immunity, 2009.
  • Chaussee, Michael. Escherichia coli O157:H7 NleH proteins bind the human ribosomal protein S3 to subvert NF-?B function.. Vol. 5, Iss. 12. PLOS Pathogens, 2009.
  • Chaussee, Michael, and . NleH proteins bind the human ribosomal protein S3 to subvert NF-?B function.. Vol. 5, Iss. 12. PLOS Pathogens, 2009.
  • Dmitriev, A V., McDowell, E J., and Chaussee, Michael. Inter- and intraserotypic variation in the Streptococcus pyogenes Rgg regulon., 43-51. Vol. 284, Iss. 1. FEMS microbiology letters, 2008. (DOI: 10.1111/j.1574-6968.2008.01171.x)
  • Chaussee, Michael, Dmitriev, A V., Callegari, E A., and Chaussee, Michael. Growth phase-associated changes in the transcriptome and proteome of Streptococcus pyogenes., 27-41. Vol. 189, Iss. 1. Archives of microbiology, 2008. (DOI: 10.1007/s00203-007-0290-1)
  • Chaussee, Michael, McDowell, E J., and Chaussee, Michael. Proteomic analysis of proteins secreted by Streptococcus pyogenes., 15-24. Vol. 431. Methods in molecular biology (Clifton, N.J.), 2008.
  • Reid, S D., Chaussee, Michael, Doern, C D., Chaussee, Michael, Montgomery, A G., Sturdevant, D E., and Musser, J M.. Inactivation of the group A Streptococcus regulator srv results in chromosome wide reduction of transcript levels, and changes in extracellular levels of Sic and SpeB., 283-92. Vol. 48, Iss. 2. FEMS immunology and medical microbiology, 2006. (DOI: 10.1111/j.1574-695X.2006.00150.x)
  • Chaussee, Michael, McDowell, E J., Rieck, L D., Callegari, E A., and Chaussee, Michael. Proteomic analysis of a penicillin-tolerant rgg mutant strain of Streptococcus pyogenes., 752-9. Vol. 58, Iss. 4. The Journal of antimicrobial chemotherapy, 2006. (DOI: 10.1093/jac/dkl319)
  • Dmitriev, A V., McDowell, E J., Kappeler, K V., Chaussee, Michael, Rieck, L D., and Chaussee, Michael. The Rgg regulator of Streptococcus pyogenes influences utilization of nonglucose carbohydrates, prophage induction, and expression of the NAD-glycohydrolase virulence operon., 7230-41. Vol. 188, Iss. 20. Journal of bacteriology, 2006. (DOI: 10.1128/JB.00877-06)
  • Wood, D N., Chaussee, Michael, Chaussee, Michael, and Buttaro, B A.. Persistence of Streptococcus pyogenes in stationary-phase cultures., 3319-28. Vol. 187, Iss. 10. Journal of bacteriology, 2005. (DOI: 10.1128/JB.187.10.3319-3328.2005)
  • Chaussee, Michael, Callegari, E A., and Chaussee, Michael. Rgg regulates growth phase-dependent expression of proteins associated with secondary metabolism and stress in Streptococcus pyogenes., 7091-9. Vol. 186, Iss. 21. Journal of bacteriology, 2004. (DOI: 10.1128/JB.186.21.7091-7099.2004)
  • Chaussee, Michael, Somerville, G A., Reitzer, L, and Musser, J M.. Rgg coordinates virulence factor synthesis and metabolism in Streptococcus pyogenes., 6016-24. Vol. 185, Iss. 20. Journal of bacteriology, 2003.
  • Somerville, G A., Chaussee, Michael, Morgan, C I., Fitzgerald, J R., Dorward, D W., Reitzer, L J., and Musser, J M.. Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival., 6373-82. Vol. 70, Iss. 11. Infection and immunity, 2002.
  • Smoot, J C., Barbian, K D., Van Gompel, J J., Smoot, L M., Chaussee, Michael, Sylva, G L., Sturdevant, D E., Ricklefs, S M., Porcella, S F., Parkins, L D., Beres, S B., Campbell, D S., Smith, T M., Zhang, Q, Kapur, V, Daly, J A., Veasy, L G., and Musser, J M.. Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks., 4668-73. Vol. 99, Iss. 7. Proceedings of the National Academy of Sciences of the United States of America, 2002. (DOI: 10.1073/pnas.062526099)
  • Chaussee, Michael, Sylva, G L., Sturdevant, D E., Smoot, L M., Graham, M R., Watson, R O., and Musser, J M.. Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes., 762-70. Vol. 70, Iss. 2. Infection and immunity, 2002.
  • Chaussee, Michael, Watson, R O., Smoot, J C., and Musser, J M.. Identification of Rgg-regulated exoproteins of Streptococcus pyogenes., 822-31. Vol. 69, Iss. 2. Infection and immunity, 2001. (DOI: 10.1128/IAI.69.2.822-831.2001)
  • McCourt, M E., Freeman, P, Tahmahkera-Stevens, C, and Chaussee, Michael. The influence of unimanual response on pseudoneglect magnitude., 52-63. Vol. 45, Iss. 1. Brain and cognition, 2001. (DOI: 10.1006/brcg.2000.1255)
  • Chaussee, Michael, Cole, R L., and van Putten, J P.. Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cells., 3226-32. Vol. 68, Iss. 6. Infection and immunity, 2000.
  • Chaussee, Michael, Ajdic, D, and Ferretti, J J.. The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production., 1715-22. Vol. 67, Iss. 4. Infection and immunity, 1999.
  • Chaussee, Michael, Wilson, J, and Hill, S A.. Characterization of the recD gene of Neisseria gonorrhoeae MS11 and the effect of recD inactivation on pilin variation and DNA transformation., 389-400. Vol. 145 ( Pt 2). Microbiology (Reading, England), 1999.
  • Chaussee, Michael, and Hill, S A.. Formation of single-stranded DNA during DNA transformation of Neisseria gonorrhoeae., 5117-22. Vol. 180, Iss. 19. Journal of bacteriology, 1998.
  • Chaussee, Michael, Phillips, E R., and Ferretti, J J.. Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion., 1956-9. Vol. 65, Iss. 5. Infection and immunity, 1997.
  • Chaussee, Michael, Stevens, D L., and Ferretti, J J.. Effects of environmental factors on streptococcal erythrogenic toxin A (SPE A) production by Streptococcus pyogenes., 551-4. Vol. 418. Advances in experimental medicine and biology, 1997.
  • Chaussee, Michael, Stevens, D L., and Ferretti, J J.. Genetic and phenotypic diversity among isolates of Streptococcus pyogenes from invasive infections., 901-8. Vol. 173, Iss. 4. The Journal of infectious diseases, 1996.
  • Gross, M D., Hays, R, Gapstur, S M., Chaussee, Michael, and Potter, J D.. Evidence for the formation of multiple types of acetaldehyde-haemoglobin adducts., 31-41. Vol. 29, Iss. 1. Alcohol and alcoholism (Oxford, Oxfordshire), 1994.
  • Chaussee, Michael, Gerlach, D, Yu, C E., and Ferretti, J J.. Inactivation of the streptococcal erythrogenic toxin B gene (speB) in Streptococcus pyogenes., 3719-23. Vol. 61, Iss. 9. Infection and immunity, 1993.
  • Callegari, Eduardo. The Streptococcal Proteome. In In, J. J. Ferretti, D. L. Stevens, and V. A. Fischetti, Eds., Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet],, edited by J. J. Ferretti, D. L. Stevens, and V. A. Fischetti. Internet (University of Oklahoma, Oklahoma City, OK.).


  • Dmietriev, A V., Zutkis, A S., Anbalagan, S, Milman, B L., Chaussee, Michael. RGG2-CONTROLLED GENE EXPRESSION IN STREPTOCOCCUS PYOGENES. Presented at the Lancefield International Conference of Streptococci and Streptococcal Diseases, Buenos Aires, Argentina. (November 2014)
  • Chaussee, Michael. Bacterial superinfections: the deadly side of influenza.
  • Bickett, Tom, Klonoski, Joshua, Mottishaw, Wendi, Dale, James, Chaussee, Michael, Sereda, Grigoriy, Huber, Victor. Contribution of vaccine-induced antibodies toward protection against influenza virus:Streptococcus pyogenes super-infection. Presented at the USD Undergraduate Research Poster Presentation, Vermillion, SD. (August 3, 2012)
  • Chaussee, Michael. Presented at the LANCEFIELD INTERNATIONAL MEETING, ITALY. (September 2011)
  • Anbalagan, Srivishnupriya, Chaussee, Michael. Rgg binding sites vary in a growth phase-dependent manner. Presented at the Mid-West Gram-Positive Pathogenesis Consortiums Meeting, Nebraska City, NE. (July 12, 2011)
  • Chaussee, Michael. Functional Genomics:  A solution to Streptococcal Disease in the 21st Century?. Presented at the The Joseph J. Ferretti Symposium: Confronting 21st Century Challenges in Infectious Disease, Oklahoma City, OK. (March 26, 2011)
  • Chaussee, Michael. Mapping regulatory networks in the flesh-eating bacterium Streptococcus pyogenes. Presented at the 8th Great Plains Infectious Disease Meeting, Kansas City, KA. (September 12, 2009)