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Dr. Wu received his B.S. degree in 2007 and M.S. degree in 20210 from Hunan University (China). Then, he moved to the University of North Dakota (UND) and obtained his Ph.D degree in Analytical Chemistry in 2015. He finished his postdoctoral training at the University of Washington and joined the UND as a research assistant professor from 2017 to 2020. From Aug 2020, he joined the department of chemistry at the USD.
Advanced Analytical Chemistry, Biochemistry, Instrumental Analysis, Synthesis and Characterization of Nanomaterials
Fluorescence biosensing and bioimaging, Nanotheranostics, Biomedicine
- Ph D, Analytical Chemistry, University of North Dakota, 2015
- MS, Biochemistry and Molecular Biology , Hunan University , 2010
- BS, Biotechnology, Hunan University , 2007
- MRI: Track 1 Acquisition of a benchtop powder X-ray diffractometer enabling research, education, and outreach in the upper Great Plains, NSF, (2025 - 2028)
- Persistant Luminescent Silicon Quantum Dots for Cellular Imaging, South Dakota Board of Regents, (2025 - 2027)
- LEAPS-MPS: Water-soluble Afterglow Luminescent Nanocomposites for Bioimaging and Bioanalysis, NSF, (2023 - 2026)
- REU Site: Molecules Meet Materials, National Science Foundation, (2022 - 2025)
- Development of upconversion nanoparticles @ semiconducting polymer dots for biofilm inhibition, NSF, State of South Dakota (Biofilm Center), (2022 - 2023)
- All-in-one nanoparticle for breast cancer treatment based on phototherapy and chemodynamic therapy, NIH, DaCCoTA, (2022 - 2023)
Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.
- Deng, X, Yang, Y, Chen, M, Liu, W, and Wu, Xu Steven. NLS-functionalized semiconducting polymer nanoparticles for enhanced intracellular accumulation and combined photodynamic-photothermal cancer therapy.. RSC advances, 2026. (DOI: 10.1039/d6ra05364e)
- He, Sherry, Liu, W, Qin, K, and Wu, Xu Steven. Red-to-NIR-Fluorescent Graphene Quantum Dots for Biomedical Applications.. Vol. 16, Iss. 7 Biosensors, 2026. (DOI: 10.3390/bios16070386)
- Wang, Dan, Tang, Le, Chen, Mingjian, Gong, Zhaojian, Fan, Chunmei, Qu, Hongke, Liu, Yixuan, Shi, Lei, Mo, Yongzhen, Wang, Yumin, Yan, Qijia, Chen, Pan, Xiang, Bo, Liao, Qianjin, Zeng, Zhaoyang, Li, Guiyuan, Jiang, Weihong, Wu, Xu Steven, and Xiong, Wei. Nanocarriers Targeting Circular RNA ADARB1 Boost Radiosensitivity of Nasopharyngeal Carcinoma through Synergically Promoting Ferroptosis, 31055-31075. Vol. 18, Iss. 45 ACS Nano, 2024. (DOI: 10.1021/acsnano.4c07676)
- Tang, L, Chen, M, Wang, D, He, Y, Ge, G, Zeng, Z, Shu, J, Guo, W, Wu, Xu Steven, and Xiong, W. Doxorubicin and Iron-doped Mesoporous Silica Nanoparticles for Chemodynamic Therapy and Chemotherapy of Breast Cancer., 17294-17309. Vol. 48, Iss. 39 New journal of chemistry = Nouveau journal de chimie, 2024. (DOI: 10.1039/d4nj03184a)
- He, Sherry, Liu, W, and Wu, Xu Steven. Semiconducting polymer dots based l-lactate sensor by enzymatic cascade reaction system., 342523. Vol. 1303 Analytica chimica acta, 2024. (DOI: 10.1016/j.aca.2024.342523)
- Han, J, Wu, Xu Steven, Zhao, J X., and Pierce, D T.. An Unprecedented Metal Distribution in Silica Nanoparticles Determined by Single-Particle Inductively Coupled Plasma Mass Spectrometry.. Vol. 14, Iss. 7 Nanomaterials (Basel, Switzerland), 2024. (DOI: 10.3390/nano14070637)
- Ge, Guili, Tu, Hanyu, Wang, Dan, Chen, Mingjian, Zeng, Zhaoyang, Guo, Can, Wu, Xu Steven, and Xiong, Wei. Fe-doped carbon dot liposome enhanced radiosensitivity of tumor cells by inducing ferroptosis, 3181-3191. Vol. 48, Iss. 7 New Journal of Chemistry, 2024. (DOI: 10.1039/d3nj04058e)
- Chen, M, Yang, Y, Tang, L, He, Sherry, Guo, W, Ge, G, Zeng, Z, Li , X, Li , G, Xiong, W, and Wu, Xu Steven. Iron-Rich Semiconducting Polymer Dots for the Combination of Ferroptosis-Starvation and Phototherapeutic Cancer Therapy., e2300839. Vol. 12, Iss. 26 Advanced healthcare materials, 2023. (DOI: 10.1002/adhm.202300839)
- Sun, D, Wu, Xu Steven, Martin, J P., Tayutivutikul, K, Du , G, Combs, C, Darland, D C., and Zhao, J X.. Streamlined synthesis of potential dual-emissive fluorescent silicon quantum dots (SiQDs) for cell imaging., 26392-26405. Vol. 13, Iss. 38 RSC advances, 2023. (DOI: 10.1039/d3ra03669c)
- Guo, W, Chen, M, Yang, Y, Ge, G, Tang, L, He, Sherry, Zeng, Z, Li , X, Li , G, Xiong, W, and Wu, Xu Steven. Biocompatibility and Biological Effects of Surface-Modified Conjugated Polymer Nanoparticles.. Vol. 28, Iss. 5 Molecules (Basel, Switzerland), 2023. (DOI: 10.3390/molecules28052034)
- He, Sherry, and Wu, Xu Steven. Ratiometric fluorescent semiconducting polymer dots for temperature sensing., 863-868. Vol. 148, Iss. 4 The Analyst, 2023. (DOI: 10.1039/d2an01717b)
- Sun, W, Sahin, N E., Sun, D, Wu, Xu Steven, Munoz, C, Thakare, J, Aulich, T, Zhang, J, Hou, X, Oncel, N, Pierce, D, and Zhao, J X.. One-Pot Synthesis of Ruthenium-Based Nanocatalyst Using Reduced Graphene Oxide as Matrix for Electrochemical Synthesis of Ammonia., 1115-1128. Vol. 15, Iss. 1 ACS applied materials & interfaces, 2023. (DOI: 10.1021/acsami.2c18413)
- Liu, Xiao, Han, Juan, Wu, Xu Steven, Pierce, David, and Zhao, Julia X.. Eu-Coordinated semiconducting polymer nanoparticles as a novel nanoprobe with two detection method signals for determination of copper(II) ions, 130194. Vol. 344 Sensors and Actuators B: Chemical, 2021. (DOI: 10.1016/j.snb.2021.130194)
- Reagen, S, Wu, Y, Liu, X, Shahni, R, Bogenschuetz, J, Wu, Xu Steven, Chu, Q R., Oncel, N, Zhang, J, Hou, X, Combs, C, Vasquez, A, and Zhao, J X.. Synthesis of Highly Near-Infrared Fluorescent Graphene Quantum Dots Using Biomass-Derived Materials for In Vitro Cell Imaging and Metal Ion Detection., 43952-43962. Vol. 13, Iss. 37 ACS applied materials & interfaces, 2021. (DOI: 10.1021/acsami.1c10533)
- Liu, Xiao, Han, Juan, Hou, Xiaodong, Altincicek, Furkan, Oncel, Nuri, Pierce, David, Wu, Xu Steven, and Zhao, Julia X.. One-pot synthesis of graphene quantum dots using humic acid and its application for copper (II) ion detection, 4991-5005. Vol. 56, Iss. 8 Journal of Materials Science, 2021. (DOI: 10.1007/s10853-020-05583-6)
- Liu, Xiao, Wu, Xu, Xing, Yuqian, Zhang, Ying, Zhang, Xuefei, Pu, Qinqin, Wu, Min, and Zhao, Julia X.. Reduced Graphene Oxide/Mesoporous Silica Nanocarriers for pH-Triggered Drug Release and Photothermal Therapy, 2577-2587. Vol. 3, Iss. 5 ACS Applied Bio Materials, 2020. (DOI: 10.1021/acsabm.9b01108)
- Wu, Xu Steven, He, Shuyi, and Zhao, Julia X.. Label-free fluorescence assay coupled exonuclease reaction and SYBR Green I for the detection of T4 polynucleotide kinase activity, 807-812. Vol. 12, Iss. 6 Analytical Methods, 2020. (DOI: 10.1039/c9ay02283j)
- Tan, Shirui, Wu, Xu, Xing, Yuqian, Lilak, Sam, Wu, Min, and Zhao, Julia X.. Enhanced synergetic antibacterial activity by a reduce graphene oxide/Ag nanocomposite through the photothermal effect, 110616. Vol. 185 Colloids and Surfaces B: Biointerfaces, 2020. (DOI: 10.1016/j.colsurfb.2019.110616)
- Xing, Y, Han, J, Wu, Xu Steven, Pierce, D T., and Zhao, J X.. Aggregation-based determination of mercury(II) using DNA-modified single gold nanoparticle, T-Hg(II)-T interaction, and single-particle ICP-MS., 56. Vol. 187, Iss. 1 Mikrochimica acta, 2019. (DOI: 10.1007/s00604-019-4057-6)
- Schroer, Zackery S., Wu, Yingfen, Xing, Yuqian, Wu, Xu, Liu, Xiao, Wang, Xu, Pino, Onnica G., Zhou, Chuanmin, Combs, Colin, Pu, Qinqin, Wu, Min, Zhao, Julia X., and Chen, Jiao. Nitrogen–Sulfur-Doped Graphene Quantum Dots with Metal Ion-Resistance for Bioimaging, 6858-6865. Vol. 2, Iss. 11 ACS Applied Nano Materials, 2019. (DOI: 10.1021/acsanm.9b01309)
- Liu, Xiao, Wu, Yingfen, Wu, Xu, and Zhao, Julia X.. A graphene oxide-based fluorescence assay for the sensitive detection of DNA exonuclease enzymatic activity, 6231-6239. Vol. 144, Iss. 21 The Analyst, 2019. (DOI: 10.1039/c9an01283d)
- Wu, Sha, Liu, Weichao, and Wu, Xu Steven, A Dual-Emission Polymer-Dots/Gold-Nanoclusters Nanohybrid for Ratiometric Fluorescence Detection of Hg²⁺. Presented at the ACS Sioux Valley Section Symposium 2026, Sioux Falls, SD. (January 2026)
- Liu, Weichao , Qin, Kang, and Wu, Xu Steven, BSA-Stabilized Polymer Dot-Gold Nanoclusters: Synthesis and Preliminary Sensing Studies. Presented at the Pittcon 2026, San Antonio, TX. (January 2026)
- Qin, Kang, Liu, Weichao, Bhatta, Naomi, Oishi, Sharmin, and Wu, Xu Steven, Co2+-Mediated Enzyme-Mimetic Activity of Amino-Functionalized SiQDs. Presented at the Pittcon 2026, San Antonio, TX. (January 2026)
- Liu, Weichao, Qin, Kang, and Wu, Xu Steven, Co³⁺-Mediated Enzyme-Mimetic Activity of Amino-Functionalized SiQDs. Presented at the Pittcon 2026, San Antonio, TX. (January 2026)
- Wu, Xu Steven, Tumor Microenvironment Responsive Semiconducting Polymer Nanoparticles for Cancer Therapy. Presented at the MRS 2025, Seattle. (January 2025)
- Wu, Xu Steven, Presented at the UND Chemistry virtual panel 24, Zoom. (January 2025)
- Wu, Xu Steven, Optical biosensing based on ratiometric fluorescent polymer dots and nanozyme. Presented at the 2024 ACS Midwest Regional Meeting, Omaha, Nebraska. (January 2024)
- Liu, Weichao , and Wu, Xu Steven, Phosphorescent Carbon Dots Doped Silica Nanomaterials via Microwave-Assisted and Modified Stöber Methods for Anti-Counterfeiting and Biosensing. Presented at the 2024 Graduate Research and Creative Scholarship Grant, Vermillion, SD. (January 2024)
- Wu, Xu Steven, Metal-doped semiconducting polymer nanoparticles for bioanalysis, plus the introduction of the Ph.D. program in USD Chemistry. Presented at the Invited Lecture, Changsha, China. (January 2024)
- Wu, Xu Steven, Semiconducting polymer nanoparticles for biomedical applications. Presented at the Invited Lecture, Hengyang, China. (January 2024)
- Liu, Weichao, He, Shuyi , and Wu, Xu Steven, Afterglow Luminescent Carbon Dots for Bioimaging and Bioanalysis. Presented at the Pittcon 2024, San Diego, Ca. (January 2024)
- He, Shuyi, Liu, Weichao, and Wu, Xu Steven, One-pot synthesis of iron doped silicon dots as a nanozyme. Presented at the Pittcon 2024, San Diego, CA. (January 2024)
- Liu, Weichao, and Wu, Xu Steven, Afterglow Luminescent Carbon Dots for Bioimaging and Bioanalysis. Presented at the 2023 ACS Sioux Valley Fall Symposium, Sioux Falls, SD. (January 2023)
- He, Shuyi, and Wu, Xu Steven, Semiconducting polymer dots L-lactate transducer by enzymatic cascade reaction system. Presented at the ACS 2023, Indianapolis, IN. (January 2023)
- He, Shuyi, and Wu, Xu Steven, Semiconducting polymer dots L-lactate transducer by enzymatic cascade reaction system. Presented at the ACS Sioux Valley 2023, Sioux Falls. (January 2023)
- He, Shuyi, and Wu, Xu Steven, Semiconducting polymer dots L-lactate transducer by enzymatic cascade reaction system. Presented at the Pittcon 2023, Philadelphia, PA. (January 2023)
- He, Shuyi, and Wu, Xu Steven, Semiconducting polymer dots L-lactate transducer by enzymatic cascade reaction system. Presented at the SDAS Annual Meeting 2022, Madison, SD. (January 2022)
- He, Shuyi, Wu, Xu Steven, and , NEAR-INFRARED SEMICONDUCTING POLYMER DOTS FOR SENSING TEMPERATURE. Presented at the Proceedings of the South Dakota Academy of Scienc (January 2021)