Originally from Taiwan, I joined the University of South Dakota Sanford School of Medicine in the summer of 2021. I am a surgeon, engineer, and multidisciplinary scientist with a career vision to improve human health, longevity, and quality of life through my research at USD.
Cardiovascular Pathophysiology, Regenerative Medicine, Synthetic and Systems Biology
My laboratory focuses on Synthetic and Systems Biology Approaches for Cardiovascular Repair and Regeneration. My research program integrates the principles and methodologies from my previous research in genetic engineering, synthetic and systems biology, and molecular cardiology at the Massachusetts Institute of Technology (MIT) and the Massachusetts General Hospital (MGH) as well as my established expertise in stem cells, biomaterials, and controlled release from my previous work at the University of Pittsburgh. My research aims to pioneer next-generation cardiovascular therapeutic and diagnostic strategies by 1) developing synthetic biology toolkits for cardiovascular disease diagnosis and treatment; 2) combining experimental and computational approaches with systems and computational biology principles to decipher high-dimensional signaling interactomes during cardiac repair and regeneration; 3) establishing transformative platform technologies for targeted cardiovascular regeneration and de novo tissue synthesis to achieve clinically significant functional recovery in diseased and aging populations.