Contact Us

Sioux Falls Campus
Health Science Center
1400 W. 22nd St.
Sioux Falls, SD 57105
Office Hours
Monday - Friday
8:00 a.m. - 5:00 p.m.


Located in the heart of South Dakota's largest city, the Sioux Falls campus resides on the campus of Sanford Health and Sanford/USD Medical Center. Conveniently located at the junction of I-29 and I-90, on the banks of the Big Sioux River, Sioux Falls is within a day's drive of most major Midwestern cities including Fargo, Kansas City, Omaha and Minneapolis/St. Paul.

The Sioux Falls campus houses medical school administration and clinical departments

  • Home to Wegner Health Sciences Library, the state's premier medical library
  • Home to our primary care ambulatory program, which is part of our family medicine department