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Neuroscience, Biochemistry, Cellular and Molecular Biology
Neurodegeneration and neuroprotection
- Postdoctoral Fellow, Neurodegeneration, Johns Hopkins University School of Medicine, 2004
- Ph D, Zoology/Neuroscience, University of Idaho, 2000
- MS, Zoology, Shandong Normal University, China, 1988
- BS, Biology, Shandong Normal University, China, 1986
- R01/RF1: Priming the proteasome to protect against aging and Alzheimer's disease (AG072510-01~05)), NIH/NIA, (2022 - 2027)
- FOXOs in ischemic stroke, NIH, (2022 - 2027)
- Alzheimer's Disease Supplement to SD INBRE (3P20GM103443-21S2), NIH/NIGMS, (2022 - 2023)
- Role of ubiquilin-1 in ischemic stroke, NIH, (2015 - 2021)
- Using mouse models to study the role of ubiquilin-1 in Alzheimer's disease, BrightFocus, (2014 - 2017)
- Studies of the Therapeutic Role of IU1 in a mouse model of ischemic stroke, NIH, (2014 - 2016)
- Role of ubiquilin‐1 in regulating learning and memory in mice, CBBRe, (2014 - 2015)
- Studies of the therapeutic role of sulforaphane in Huntington's disease mice, SSOM (USD), (2014 - 2015)
- Development and validation of therapeutic reagents for treating Huntington's disease, ORSP , (2013 - 2014)
- Modeling pathogenesis of Huntington's disease using patient-derived iPS cells, NIH, (2011 - 2015)
- Role of Ubiquilin in ischemic stroke, SDBOR, (2011 - 2012)
- Characterization and functional studies of novel Htt-interacting proteins, ORSP, (2010 - 2011)
Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.
- Huber, Christa C., Callegari , Eduardo E., Paez, Maria M., Romanova , Svetlana , and Wang, Hongmin. Heat Shock-Induced Extracellular Vesicles Derived from Neural Stem Cells Confer Marked Neuroprotection Against Oxidative Stress and Amyloid-β-Caused Neurotoxicity. Mol Neurobiol, 2022. (DOI: 10.1007/s12035-022-03055-3)
- Hart, Hannah H., Valentin , Madeline M., Peters, Stephanie S., Holler, Susan S., Wang, Hongmin, Harmon , Aaron A., and Holler, Larry L.. The cytoprotective role of GM1 ganglioside in Huntington disease cells.. Mol Biol Rep , 2022. (DOI: doi: 10.1007/s11033-022-07830-2)
- Huber, C C., Wang, Xuejun, and Wang, Hongmin. Impact of Cardiovascular Diseases on Ischemic Stroke Outcomes., 138. Vol. 21, Iss. 5 Journal of integrative neuroscience, 2022. (DOI: 10.31083/j.jin2105138)
- Liu, Y, Subedi, K, Baride, Aravind, Romanova, S, Callegari, E, Huber, C C., Wang, Xuejun, and Wang, Hongmin. Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury., 29. Vol. 18, Iss. 1 Journal of Neuroinflammation, 2021. (DOI: 10.1186/s12974-021-02081-7)
- Wang, Xuejun, and Wang, Hongmin. Priming the Proteasome to Protect against Proteotoxicity, 639-648. Vol. 26, Iss. 7 Trends in Molecular Medicine, 2020. (DOI: 10.1016/j.molmed.2020.02.007)
- Liu, Yanying, Feng, Shelley , Subedi, Kalpana , and Wang, Hongmin. Attenuation of Ischemic Stroke-Caused Brain Injury by a Monoamine Oxidase Inhibitor Involves Improved Proteostasis and Reduced Neuroinflammation, 937-948. Vol. 57, Iss. 2 Mol Neurobiol , 2020. (DOI: doi: 10.1007/s12035-019-01788-2)
- Liu, Yanying, and Wang, Hongmin. Disrupted blood-brain barrier in 5×FAD mouse model of Alzheimer's disease can be mimicked and repaired in vitro with neural stem cell-derived exosomes . Vol. S0006-291X(20)30342-9. Biochem Biophys Res Commun , 2020. (DOI: 10.1016/j.bbrc.2020.02.074)
- Liu, Yanying, and Wang, Hongmin. Modeling Sporadic Alzheimer's Disease by Efficient Direct Reprogramming of the Elderly Derived Disease Dermal Fibroblasts into Neural Stem Cells , 919-933. Vol. 73, Iss. 3 J Alzheimers Dis , 2020. (DOI: doi: 10.3233/JAD-190614)
- Liu, Yanying, Min, Jia-Wei, Feng, Shelley, Subedi, Kalpana, Qiao, Fangfang, Mammenga, Emily, Callegari, Eduardo, and Wang, Hongmin. Therapeutic Role of a Cysteine Precursor, OTC, in Ischemic Stroke Is Mediated by Improved Proteostasis in Mice. Transl Stroke Res, 2019. (DOI: doi: 10.1007/s12975-019-00707-w)
- Hu, C, Tian, Y, Xu, H, Pan, B, Terpstra, E E., Wu, P, Wang, Hongmin, Li , F, Liu, J, and Wang, Xuejun. Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury.. The Journal of Clinical Investigation, 2018. (DOI: 10.1172/JCI98287)
- Min, Jia-Wei, Liu, Yanying, Wang, David, Qiao, Fangfang, and Wang, Hongmin. The non-peptidic δ-opioid receptor agonist Tan-67 mediates neuroprotection post-ischemically and is associated with altered amyloid precursor protein expression, maturation and processing in mice, 336-347. Vol. 144, Iss. 3 J Neurochem, 2018. (DOI: 10.1111/jnc.14265)
- Liu, Y, Qiao , F, Leiferman , P P., Ross, A, Schlenker, E E., and Wang, Hongmin. FOXOs modulate proteasome activity in human induced pluripotent stem cells of Huntington's disease and their derived neural cells. Vol. ddx327 Hum Mol Genet, 2017.
- Adegoke, O ., Qiao , F, Liu , Y, Longley , K, Feng , S, and Wang, Hongmin. Overexpression of ubiquilin-1 alleviates Alzheimer's disease-caused cognitive and motor deficits and reduces β-amyloid accumulation in mice, Jun 8. Vol. 2017 J Alzheimer's Dis. , 2017. (DOI: 3233/ JAD-170173. [Epub ahead of print].)
- Qiao , F, Longley, K K., Feng, S, Schnack , S, Gao, H, Li, Y, Schlenker, E ., and Wang, Hongmin. Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins, pii: e13260. . Vol. 5, Iss. 8 Physiol Rep., 2017. (DOI: 10.14814/phy2.13260)
- Min, J, Lu, L, Freeling , J J., Martin, D, and Wang, Hongmin. USP14 Inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice, 826-833.. Vol. 140, Iss. 5 J Neurochem, 2017.
- Liu, Y, Qiao, F, and Wang, Hongmin. Enhanced proteostasis in post-ischemic stroke mouse brains by ubiquilin-1 promotes functional recovery, Dec 7. [Epub ahead of print].. Vol. 2016 Cell Mol Neurobiol. , 2016.
- Sane, Sanam, Abdullah, Ammara, Nelson, Morgan, Wang, Hongmin, Chauhan, Subhash S., Newton, Samuel, and Rezvani, Khosrow. Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy., Editors Helen Neumann. Storrs, Connecticut: Cell Stress Chaperones / Springer, 2015. (DOI: 10.1007/s12192-015-0661-5)
- Rezvani, Khosrow, Abdullah, Ammara, Sane, Sanam, Freeling, Jessica , Wang, Hongmin, and Zhang, Dong . Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis During DNA Damage Stresses in Colon Cancer Cells., 1066-78. Vol. 3, Iss. 6(11) Journal of Cancer, 2015. (DOI: 10.7150/jca.12134)
- Rezvani, Khosrow, Abdullah, Ammara, Sane, Sanam, Branik, Kate , Freeling, Jessica , Wang, Hongmin, and Zhang, Dong. A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2, 23561-81. Vol. 6, Iss. 27 Oncotarget, 2015.
- Zou, Jianqiu, Zhang, Deli , Qin, Guang , Chen, Xiangming , Wang, Hongmin, and Zhang, Dong . BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1, 3685-97. Vol. 13, Iss. 23 Cell Cycle, 2014. (DOI: 10.4161/15384101.2014.964973)
- Liu, Yanying, Xue, Yuanchao, Ridley, Samantha , Zhang, Dong, Rezvani, Khosrow , Fu, Xuang-Dong, and Wang, Hongmin. Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formation, e109621. Vol. 9, Iss. 10 PLOS ONE, 2014. (DOI: 10.1371/journal.pone.0109621)
- Liu, Y., Hettinger, C. C., Zhang, Dong, Rezvani, Khosrow, Wang, Xuejun, and Wang, Hongmin. Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease, 539-47. Epub 2014 Jan 18.. Vol. 129, Iss. 3 J Neurochem, 2014. (DOI: 10.1111/jnc.12647)
- Liu, Y., Hettinger, C. C., Zhang, Dong, Rezvani, Khosrow, Wang, Xuejun, and Wang, Hongmin. The Proteasome Function Reporter GFPu Accumulates in Young Brains of the APPswe/PS1dE9 Alzheimer's Disease Mouse Model, 315-322. Epub 2013 Dec 21. . Vol. 34, Iss. 3 Cell Mol Neurobiol, 2014. (DOI: 10.1007/s10571-013-0022-9)
- Rezvani, Khosrow, Zhang, Dong, Wang, Hongmin, Telleria, Carlos, and Schlenker, Evelyn. Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin2 interactions in colon cancer cells ., Editors Dr Giovanni Melillo. Rome: Cell death and Disease/Nature publishing group, 2014.
- Liu, Y., Lü , L., Hettinger, C. C., Dong, G., Zhang, Dong, Rezvani, Khosrow, Wang, Xuejun, and Wang, Hongmin. Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice, 2813-21. Vol. 34, Iss. 8 J Neurosci, 2014. (DOI: 10.1523/JNEUROSCI.3541-13.2014)
- Zou, Jianqiu, Tian, Fen, Li, Ji, Pickner, Wyatt, Long, Molly, Rezvani, Khosrow, Wang, Hongmin, and Zhang, Dong. FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. , 1022. Vol. 2 Biology Open , 2013.
- Tian, Fen, Sharma, Shilpy, Zou, Jianqiu, Lin, Shiaw-Yih, Wang, Bin, Rezvani, Khosrow, Wang, Hongmin, Parvin, Jeffery J., Ludwig, Thomas, Canman, Christine C., and Zhang, Dong. BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade, 13558. Vol. 110, Iss. 33 Proc Natl Acad Sci U S A, 2013.
- Zou, Jianqiu, Rezvani, Khosrow, Wang, Hongmin, Lee, Kyung K., and Zhang, Dong. BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress, 2255. Vol. 12, Iss. 14 Cell Cycle, 2013.
- Dong, G, Gross, K, Qiao, F, Ferguson , J, Callegari, E E., Rezvani , K, Zhang, D , Gloeckner , C C., Ueffing , M, and Wang, Hongmin. Calretinin interacts with huntingtin and reduces mutant huntingtin-caused cytotoxicity (2012). Vol. 2012, Iss. Aug 14 [Epub ahead of print] J Neurochem, 2012. (DOI: 10.1111/j.1471-4159.2012.07919.x)
- Rezvani, Khosrow, Baalman, K, Yang, Y, Mee, M, Dawson, S, Wang, Hongmin, De Biasi, M, and mayer, J. Proteasomal Degradation of the Metabotropic Glutamate Receptor 1is Mediated by Homer-3 via the Proteasomal S8 ATPase., Editors Jörg Schulz, 24-37. Vol. 122, Iss. 1 Journal of Neurochemistry, 2012. (DOI: 10.1111/j.1471-4159.2012.07752.x)
- Rezvani, K, Baalman, K, Teng, Y, Mee, M M., Dawson, S S., Wang, Hongmin, De Biasi, M, and Mayer, R R.. Proteasomal degradation of the metabotropic glutamate receptor 1α is mediated by Homer-3 via the proteasomal S8 ATPase: Signal transduction and synaptic transmission (2012), 24-37. Vol. 122, Iss. 1 J Neurochem, 2012. (DOI: 10.1111/j.1471-4159.2012.07752.x)
- Dong, Gaofeng, Callegari , Eduardo E., Gloeckner , C C., Ueffing , M, and Wang, Hongmin. Mass spectrometric identification of novel posttranslational modification sites in Huntingtin (2012), 2060-4. Vol. 12, Iss. 12 Proteomics, 2012. (DOI: 10.1002/pmic.201100380)
- Lu, Lanhai, and Wang, Hongmin. Transient focal cerebral ischemia upregulates immunoproteasomal subunits (2012), 965-70. Vol. 32, Iss. 6 Cell Mol Neurobiol, 2012.
- Dong, G, Callegari , E E., Gloeckner , C C., Ueffing, M, and Wang, Hongmin. Prothymosin-α interacts with mutant Huntingtin and suppresses its cytotoxicity in Cell culture, 1279-89 . Vol. 287, Iss. 2 J Biol Chem, 2012.
- Dong, Gaofeng, Ferguson, Justin J., Duling, A A., Nicolas, R R., Zhang, Dong, Rezvani, Khosrow, Fang, S, Monterio, M M., Li, S, Li, X X., and Wang, Hongmin. Modeling Pathogenesis of Huntington's Disease with Inducible Neuroprogenitor Cells, 737. Vol. 31 Cell Mol Neurobiol , 2011.
- Wang, Hongmin, Karbowski , M, and Monteiro , M M.. Mitochondrial dynamics and Huntington's disease: A dance of fate., Editors Bingwei Lu, 235-257. Springer Press: Mitochondrial Dynamics and Neurodegeneration, 2011.
- Lim, P P., Danner, R, Liang, J , Doong, H, Harman, C, Srinivasan, D, Rothenberg, C, Wang, Hongmin, Ye, Y, Fang, S, and Monteiro, M M.. Ubiquilin and p97/VCP bind erasin forming a complex involved in ERAD . In J. Cell Biol. 2009 Oct 19;187(2):201-17. , 201-17. Vol. 187, Iss. 2 J Cell Biol, 2009.
- Wang, Hongmin, Lim, P P., Karbowski , M, and Monteiro, M M.. Effects of overexpression of huntingtin on mitochondrial integrity , 737-52. Vol. 18, Iss. 4 Hum Mol Genet , 2009.
- Wang, Hongmin, and Monteiro, M M.. Ubiquilin enhances expanded polyglutamine degradation, 423-7. Vol. 360, Iss. 2 Biochem Biophys Res Commun, 2007.
- Wang, Hongmin, and Monteiro, M M.. Ubiquilin overexpression reduces GFP-polyalanine-induced protein aggregates and toxicity, 2810-20.. Vol. 313, Iss. 13 Exp Cell Res , 2007.
- Yu, S S., Andrabi (co-first authors), S. S., Wang, Hongmin, Kim, N N., Poirier, G G., Dawson , V V., and Dawson, T T.. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death , 18314-9. Vol. 103, Iss. 48 Proc Natl Acad Sci USA , 2006.
- Andrabi , S. S., Kim (co-first authors), N N., Yu, S S., Wang, Hongmin, Koh, D D., Sasaki, M, Klaus, J J., Otsuka, T, Zhang, Z, Koehler, R R., Hurn, P P., Poirier, G G., Dawson, V V., Dawson, T T., and . Poly(ADP-ribose) (PAR) polymer is a death signal , 18308-13. Vol. 103, Iss. 48 Proc Natl Acad Sci USA , 2006.
- Wang, Hongmin, Yin, C, Lim, P P., Reickher, M, Vogel, B B., and Monteiro, M M.. Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin , 1025-1041. Vol. 15 , Iss. 6 Hum Mol Genet, 2006.
- Wang, Hongmin, Yu, S S., Koh, D D., Lew, J, Coombs, C, Bowers, W, Federoff, H H., Poirier, G G., Dawson , T T., Dawson, V V., and . Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death, 10963-73. Vol. 24 , Iss. 48 J Neurosci, 2004.
- Yue, J, Shi, W, Xie, J, Li , Y, Zeng, Erliang, Liang, L, and Wang, Hongmin. Detection of rifampin-resistant Mycobacterium tuberculosis strains by using a specialized oligonucleotide microarray, 47-54. Vol. 48, Iss. 1 Diagnostic microbiology and infectious disease, 2004. (DOI: 10.1016/j.diagmicrobio.2003.08.005)
- Yu, S S., Wang, Hongmin, Dawson , T T., Dawson, V V., and . Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity , 303-17. Vol. 14, Iss. 3 Neurobiol. Dis. , 2003.
- Sheline, C C., Wang, Hongmin, Cai, A-L, Dawson , V V., and Choi, D D.. Involvement of poly-ADP ribosyl polymerase-1 in fast but not slow zinc neurotoxicity , 1402-9. Vol. 8, Iss. 6 Eur J Neurosc, 2003.
- Wang, Hongmin, Shimoji, M, Yu, S S., Dawson , T T., and Dawson, V V.. Apoptosis inducing factor and PARP mediated injury in the MPTP mouse model of Parkinson's disease. Parkinson's disease: the Life Cycle of the Dopamine Neuron , 132-140. Vol. 991 Annals of New York Acad Sci, 2003.
- Yue, J, Shi, W, Xie, J, Li , Y, Zeng, Erliang, and Wang, Hongmin. Mutations in the rpoB gene of multidrug-resistant Mycobacterium tuberculosis isolates from China, 2209-12. Vol. 41, Iss. 5 Journal of clinical microbiology, 2003.
- Wang, Hongmin, Yu* (co-first author), S S., Poitras, M M., Coombs, C, Bowers, W W., Federoff, H H., Poirier, G G., Dawson, T T., and Dawson , V V.. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor , 259-263. Vol. 297, Iss. 5579 Science, 2002.
- Wang, Hongmin, Chadaram, S S., Norton, A A., and Laskowski, M M.. Development of inhibition by ephrin-A5 on outgrowth of embryonic spinal motor neurites , 233-243. Vol. 47 , Iss. 3 J Neurobiol , 2001.
- Laskowski, M M., Feng (co-first authors), , G, Feldheim, D D., Wang, Hongmin, Lewis, R, Frisen, J, Flanagan, J J., and Sanes, J J.. Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers, 295-306. Vol. 25, Iss. 2 Neuron, 2000.
- Wang, Hongmin, Chadaram, S S., Norton, A A., Lewis, R, Boyum, J, Trumble, W, Sanes, J J., and Laskowski, M M.. Positionally selective growth of embryonic spinal cord neurites on muscle membranes , 4984-4993. Vol. 19 4984-4993, Iss. 12 J Neurosci, 1999.
- Amenomori, M, Cao, Z, Ding, L L., Feng, Z Z., Hibino, K, Hotta, N, Huang, Q, Huo, A A., Jia, H H., Jiang, G G., Jiao, S S., Kajino, F, Kasahara, K, Labaciren, Mei, Dongming, Meng, L, Meng, X X., Mimaciren, Mizutani, K, Mu, J, Nanjo, H, Nishizawa, M, Nusang, Oguro, A, Ohnishi, M, Ohta, I, Ren, J J., Saito, T, Sakata, M, Shi, Z Z., Shibata, M, Shirai, T, Sugimoto, H, Sun, X X., Tai, A, Taira, K, Tan, Y Y., Tateyama, N, Torii, S, Wang, Hongmin, Wen, C C., Yamamoto, Y, Yao, X X., Yu, G G., Yuan, P, Yuda, T, Zeng, J J., Zhang, Chao, Zhang, H H., Zhang, L, Zhasang, Zhaxiciren, and Zhou, W W.. Cosmic-ray deficit from the directions of the Moon and the Sun detected with the Tibet air-shower array., 2675-2681. Vol. 47, Iss. 7 Physical review D: Particles and fields, 1993.
- Amenomori, M, Cao, Z, Ding, L L., Feng, Z Z., Hibino, K, Hotta, N, Huang, Q, Huo, A A., Jia, H H., Jiang, G G., Jiao, S S., Kajino, F, Kasahara, K, Labaciren, Mei, Dongming, Meng, L, Meng, X X., Mimaciren, Mizutani, K, Mu, J, Nanjo, H, Nishizawa, M, Nusang, Oguro, A, Ohnishi, M, Ohta, I, Ren, J J., Saito, T, Sakata, M, Shi, Z Z., Shibata, M, Shirai, T, Sugimoto, H, Sun, X X., Tai, A, Taira, K, Tan, Y Y., Tateyama, N, Torii, S, Wang, Hongmin, Wen, C C., Yamamoto, Y, Yao, X X., Yu, G G., Yuan, P, Yuda, T, Zeng, J J., Zhang, Chao, Zhang, H H., Zhang, L, Zhasang, Zhaxiciren, and Zhou, W W.. Search for steady emission of 10-TeV gamma rays from the Crab Nebula, Cygnus X-3, and Hercules X-1 using the Tibet air shower array., 2468-2471. Vol. 69, Iss. 17 Physical review letters, 1992. (DOI: 10.1103/PhysRevLett.69.2468)
- Donald S. MacKay Distinguished Professor of Research, SSOM, 2015
- Hu, Chengjun, Tian, Yihao, Xu, Hongxin, Pan, Bo, Wu, Penglong, Li, Faqian, Wang, Hongmin, and Wang, Xuejun, INADEQUATE COUPLING BETWEEN UBIQUITINATION AND THE PROTEASOME CONTRIBUTES TO MYOCARDIAL ISCHEMIA/REPERFUSION INJURY. Presented at the The 20th Annual meeting of Nebraska Physiological Society (NPS), Omaha, NE. (October 28, 2017)
- Schnack, Sabrina, Gao, Hongbo, Wang, Hongmin, and Li, Yi-Fan, . Alterations Of Growth And Metabolism Related Proteins In Skeletal Muscles Of Ubiquilin-1 Transgenic Mice. Presented at the Nebraska Physiological Society Annual Conference, Vermillion, SD. (October 2015)
- Wang, Hongmin, Validation of ubiquilin-1 as a neuroprotective target for ischemic stroke . Presented at the Stroke Symposium: Research Frontiers in Cerebrovascular Disease and Disorders, Sioux Falls, SD. (October 01, 2015)
- Wang, Hongmin, Induced pluripotent stem cells in studies of Huntington's disease. Presented at the Annual Research Symposium of the Center for Brain and Behavior Research (CBBRe) of the University of South Dakota, Vermillion, SD. (August 18, 2015)
- Nelson, Morgan, sane, sanam, Wang, Hongmin, and Rezvani, Khosrow, Identification and Characterization of Multiple Distinct Proteasome Subpopulations in Brain Regions . Presented at the Center for Brain and Behavior Research (CBBRe) 2014 Symposium, Vermillion, SD. (August 21, 2014)
- Wang, Xuejun, Hu, Chengjun, Tian, Yihao, and Wang, Hongmin, Inadequate Coupling between Ubiquitination and the Proteasome is a Major Pathogenic Factor of Myocardial Ischemia/Reperfusion Injury. Presented at the Basic Cardiovascular Sciences 2014 Scientific Sessions: Pathway to Cardiovascular Therapeutics, Las Vegas, NV. (July 16, 2014)
- Hu, Chengjun, Wang, Xuejun, Wang, Hongmin, and Tian, Yihao, Inadequate Coupling between Ubiquitination and the Proteasome is a Major Pathogenic Factor of Myocardial Ischemia/Reperfusion Injury. Presented at the The First Annual ACRE/APS Sympoisum, Las Vegas, NV. (July 13, 2014)
- Wang, Hongmin, Identification and validation of therapeutic compounds for treating Huntington's disease. Presented at the 3rd Protein Quality Control and Degradation (PQCD) Symposium, Deadwood, SD. (June 05, 2014)
- Liu, Y, Lü, L, Dong, G, Hettinger, C, Watt, M, Forster , G, Wang, X, and Wang, Hongmin, Ubiquilin protects cells against oxidative stress and ischemic stroke caused injury in mice. Presented at the Annual Neuroscience Meeting, San Diego, CA. (November 13, 2013)
- Qiao, F, Liu, Y, and Wang, Hongmin, Generation and characterization of transgene- and virus-free inducible pluripotent stem cells derived from Huntington's disease patient fibroblasts. Presented at the Annual Neuroscience Meeting, San Diego, CA. (November 11, 2013)
- Hettinger , C L., Liu, Y, Dong,, G, Lü, L, Wang, X, Watt, M, Forster, G, and Wang, Hongmin, Ubiquilin suppresses accumulation of mutant Huntingtin and motor deficits in HD mice. Presented at the Annual Neuroscience Meeting, San Diego, CA. (November 10, 2013)
- Wang, Hongmin, Role of Ubiquilin in Huntington's Disease. Presented at the HD2012, Boston MA. (August 2012)
- Lu, L, Hettinger, C, Dong, G, Jahn, A, Wang, X, Watt, M, Forster, , G, and Wang, Hongmin, Characterization of Huntington's Disease Mice Deficient in the Ubiquilin Gene . Presented at the Ubiquitin, Protein Quality Control and Molecular Pathogenesis Symposium, Deadwood SD. (June 2012)
- Wang, Hongmin, Role of Ubiquilin in Huntington's Disease . Presented at the Ubiquitin, Protein Quality Control and Molecular Pathogenesis Symposium, Deadwood SD. (June 2012)
- Dong, G, Hettinger, C, Watt, M, Forster , G, and Wang, Hongmin, Overexpression of Ubiquilin Reduces Mutant Huntingtin Caused toxicity in Huntington's Disease Mice. Presented at the Sanford Health - USD Biomedical Research Symposium, Vermillion SD. (May 2012)
- Gross, Kylie, and Wang, Hongmin, Calretinin interacts with and reduces mutant huntingtin-caused toxicity. Presented at the Annual Cell Biology Meeting, Denver, CO. (December 2011)
- Dong, Gaofeng, and Wang, Hongmin, Prothymosin-alpha interacts with and reduces mutant huntingtin-caused toxcity in cell culture . Presented at the Annual Neuroscience Meeting, Washington DC. (November 2011)