Faculty and staff at the University of South Dakota invite you to see what research is available to your business. Key USD research areas include materials chemistry, physics and neuroscience. Our biomedical engineering department is performing cutting edge research in tissue regeneration, medical devices and antimicrobial materials. Our chemistry department works with collaborators across the state on photovoltaics research. Germanium crystal growth and underground lab experiments accent USD physics research. Innovative Posttraumatic Stress Disorder (PTSD) research affecting veterans and the effects of stress on the brain are just part of the collaborative efforts in our neurobehavioral science arena. Unique collaboration opportunities are available with a number of departments including the Native American studies department and the National Music Museum, which is located on the campus of USD. Other areas of expertise include rural medicine, social work, political science and education.

Antimicrobial Materials

Antimicrobial Textiles

A system for delivering, stabilizing, and storing hypochlorite and/or hypobromide salts that gives textiles antimicrobial properties that can be recharged upon exposure to chlorine bleach.

Learn more about hypohalide salts

Advanced Materials Production

Germanium Crystal Growth

High purity germanium crystals can be used in dark matter detection experiments; the sensitivity of detectors is proportional to the size of the crystal, so being able to produce larger crystals is a distinct advantage to this technology.

Learn more about germanium crystals

Carbon Fiber-Reinforced Polymer

A method for the preparation and functionalization of carbonaceous materials, facilitating their grafting into polymer matrices. The method does not break any carbon-carbon bond, which preserves structural integrity of the carbon fiber component.

Learn more about carbon fiber

Preventative Medicine

Chimeric Influenza Vaccine

A protein-based vaccine that has the ability to induce a broad immune response against genetically diversified influenza viruses, produced by using a DNA shuffling technology.

Learn more about influenza A flu vaccine

Dental Innovations

Antifungal Dentures

A rechargeable, long-term antifungal product for dentures, specifically designed with Candida-associated denture stomatitis in mind.

Learn more about antifungal dentures

Sequential Material Deposition for the Remineralization and Desensitization of Teeth

Positively and negatively charged components contained in different dentifrices (e.g. toothpaste, mouth rinse) are deposited on the tooth surface by sequential application in order to remineralize and desensitize teeth.

Learn more about remineralization and desensitization of teeth

Medical Devices

Drug Loading Method for PGS

An organic solvent-based drug loading method for Poly(glycerol sebacate), a polymer that can be implanted and used as a tissue regeneration scaffold in the human body

Learn more about biopolymer drug loading method

Drug-Coated Balloon Catheters

Specific coatings on balloon catheters enable more control over when drugs are released and what drug concentrations are applied to tissue.

Nanomaterials and Security Inks

These technologies were developed in collaboration with South Dakota School of Mines and Technology.

Printing with Upconverting Nanoparticles - Use of upconverting inks in QR codes enables the use of QR codes for security purposes and to achieve higher levels of security than are currently available.

Aerosol-Jet Printable Optically Variable Ink - A process that helps stabilize (keep dispersed) aqueous-based mixtures of nanoparticles used for ink formulation or other particle-based delivery methods.

Upconverting Nanoparticle Ink Reader Apparatus - A device used to read and decode covert codes printed with upconverting nanoparticle inks.

Learn more about these technologies

Molecular Super Containers and Their Applications


A new class of container molecule featuring well-defined endo and exo cavities, these molecules mimic the structure of viruses. They also show high adsorption capacity and selectivity for different chemical systems.

Learn more about metal organic super containers

IonSensors using MOSCs - Sensors that can detect specific ions due to the tunability of the included metal organic supercontainers.

Photovoltaics and Optoelectronics

Fluorinated Aromatics

Fluorinated aromatic materials replace problematic elements in current optoelectronics including organic solar cells increasing stability and efficiency.

Learn more about fluorinated aromatic materials

Electron-Deficient Fluorous Porphyrins

A novel process for the preparation and use of a molecule that has the dual function of light harvesting and accepting or donating electrons making it ideal for organic solar cell applications.

Learn more about electron-deficient fluorous porphyrins


Contact Us

Contact the Office of Research & Sponsored Programs (orsp@usd.edu) for inquiries regarding specific areas of expertise and available research equipment and facilities.

The USD Technology Transfer Office can assist you and your business in finding the research and collaborative resources at USD to fit your specific needs. From expertise, proposal collaborations and available technologies, USD has what you need to be successful. Please contact the Technology Transfer Office at TTO@usd.edu or at 605-677-6229 with any questions.