Due to the rapidly growing faculty research in the area of Protein Quality Control and Degradation (PQCD) at the Sanford School of Medicine of the University of South Dakota, this three-day conference will focus on the role of the ubiquitin-proteasome system (UPS) and autophagy in cardiovascular disease, neural degeneration and cancer biology. In addition, a series of general discussions and poster sessions will provide participants an opportunity to network with researchers and field experts.

State-of-the-art lectures from world-renowned scientists and presentations by the Protein Quality Control Degradation faculty of the Sanford School of Medicine will cover diverse topics related to protein quality control and their relevance to disease pathogenesis. Invited speakers include Ivor J. Benjamin, M.D., of the University of Utah (Reductive Stress and Proteostasis); George DeMartino, Ph.D., University of Texas Southwestern (Regulation of Proteasome Assembly, Activation and Function); Mark Hochstasser, Ph.D., of Yale University (Biogenesis of Proteasomes): Peipei Ping, Ph.D., UCLA (Proteasome Regulation by PTMs); and X. William Yang, M.D., Ph.D., of University of California, Los Angeles (Designer Mouse Models to Dissect Huntington’s Disease).

For more information, please contact Andrea Jahn at (605) 677-8859 or e-mail: PQCD@usd.edu. Visit www.usd.edu/biomed for a complete schedule of events and a registration form.

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